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Pathological features of rats in CIA and normal groups. a, b) immunofluorescence analyses of CD86 macrophages (green), immunohistochemical analyses, iNOS expression, and TRAP staining of osteoclast number in joints, micro-CT images of ankles respectively. c, d) Quantitative micro-CT analysis of BMD and BS/BV (n = 3). **P < 0.01, ***P < 0.001.
