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Interaction Energy (kcal/mol) between RBD Residues (Wild Type, Delta Variant, and Omicron Variant) and ACE2, Categorized as Weak (>−2 kcal/mol), Medium (−5 kcal/mol to −2 kcal/mol), or Strong (<−5 kcal/mol). Residue interaction extents with ACE2: W (Weak), M (Medium), and S (Strong). The RBD mutation residues with significant interaction changes concerning those of wild type are highlighted in red and bold.
