Table 1.
Profiles of exposure and outcomes in GWAS datasets.
| Trait | GWAS ID (Data sources) | Data Type | Case | Control | Ethnicity | Consortium |
|---|---|---|---|---|---|---|
| T2DM | PMID: 35551307 | Exposure | 74,124 | 824,006 | European | DIAMANTE |
| T2DM | PMID: 35551307 | Exposure | 77,418 | 356,122 | East Asian | DIAMANTE |
| NAFLD | finngen_R9_NAFLD | Outcome | 2,275 | 375,002 | European | FinnGen biobank |
| HCC | finngen_R9_C3_HEPATOCELLU_CARC_EXALLC | Outcome | 453 | 287,137 | European | FinnGen biobank |
| Viral Hepatitis | finngen_R9_AB1_VIRAL_HEPATITIS | Outcome | 2,143 | 375,134 | European | FinnGen biobank |
| HBV | finngen_R9_K11_CHRONHEP | Outcome | 885 | 366,450 | European | FinnGen biobank |
| HCV | GCST90041714(PMID: 34737426) | Outcome | 219 | 456,129 | European | GWAS catalog |
| ALT | bbj-a-6(PMID: 29403010) | Outcome | 134,182 | East Asian | Biobank Japan | |
| AST | bbj-a-8(PMID: 29403010) | Outcome | 134,154 | East Asian | Biobank Japan | |
| HCC | bbj-a-158(PMID: 32514122) | Outcome | 1,866 | 195,745 | East Asian | Biobank Japan |
| Viral Hepatitis | GCST90246018(PMID: 37601966) | Outcome | 117 | 75,764 | East Asian | GWAS catalog |
| HBV | GCST90018584(PMID: 34594039) | Outcome | 2,234 | 169,588 | East Asian | GWAS catalog |
| HCV | GCST90018585(PMID: 34594039) | Outcome | 7,110 | 169,588 | East Asian | GWAS catalog |
GWAS, genome-wide association study; ID, identity; T2DM, type 2 diabetes mellitus; DIAMANTE, Diabetes Meta-analysis of Trans-ethnic Association Studies; NAFLD, non-alcoholic fatty liver disease; HCC, hepatocellular carcinoma; HBV, hepatitis B virus; HCV, hepatitis C virus; ALT, Alanine aminotransferase; AST, Aspartate aminotransferase.