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Alignment of the deduced amino acid sequences of the variable domains of the heavy and κ chains. Substitutions relative to either Fab 101 or 201 are shown in single amino acid code. Identical residues are indicated by dashes. Amino acids are numbered in accordance with Kabat et al. (21), and complementary determining regions (CDR1, CDR2, and CDR3) and framework regions (FR1, FR2, FR3, and FR4) are shown above the sequence alignments.
