Table 1.
Baseline characteristics of the cohort
| COPDGene | |||
| Subgroup | Visit 1 | Visit 2 | |
| n | 411 | 411 | |
| Age (years) (mean (SD)) | 62.5 (8.6) | 68.0 (8.6) | |
| Gender (%) | Male | 192 (46.7) | 192 (46.7) |
| Female | 219 (53.3) | 219 (53.3) | |
| Race (%) | White | 389 (94.6) | 389 (94.6) |
| Black | 22 (5.4) | 22 (5.4) | |
| Smoking status (%) | Former smoker | 282 (68.6) | 312 (76.3) |
| Current smoker | 129 (31.4) | 97 (23.7) | |
| Pack-years (mean (SD)) | 41.9 (24.7) | 42.7 (25.2) | |
| Body mass index (kg/m2) (mean (SD)) | 29.2 (5.7) | 29.1 (6.2) | |
| Time from baseline visit (years) (mean (SD)) | – | 5.5 (0.7) | |
| Percentage of lung occupied by interstitial features (median (IQR)) | 4.4 (2.9–6.9) | 4.0 (2.2–6.5) | |
| Percentage of lung occupied by emphysema (median (IQR)) | 0.9 (0.2–6.9) | 0.4 (0.1–4.8) | |
| Percentage of lung occupied by normal parenchyma (median (IQR)) | 92.7 (83.9–95.8) | 93.6 (83.6–96.5) | |
| PLuSS | |||
| Subgroup | First visit | Last visit | |
| n | 95 | 95 | |
| Age (years) (mean (SD)) | 64.4 (6.6) | 73.1 (6.2) | |
| Gender (%) | Female | 21 (22.1) | 21 (22.1) |
| Male | 74 (77.9) | 74 (77.9) | |
| Race (%) | American Indian/Alaskan Native | 0 (0.0) | 0 (0.0) |
| Asian | 0 (0.0) | 0 (0.0) | |
| Black | 5 (5.3) | 5 (5.3) | |
| Pacific Islander | 0 (0.0) | 0 (0.0) | |
| White | 90 (94.7) | 90 (94.7) | |
| Smoking status (%) | Former smoker | 43 (45.3) | Unavailable |
| Current smoker | 52 (54.7) | Unavailable | |
| Pack-years (mean (SD)) | 76.0 (25.1) | Unavailable | |
| Body mass index (kg/m2) (mean (SD)) | 28.0 (5.3) | 27.7 (5.1) | |
| Time from baseline visit (years) (mean (SD)) | – | 8.8 (2.7) | |
| Percentage of lung occupied by interstitial features (median (IQR)) | 14.4 (11.0–18.8) | 14.8 (11.7–17.8) | |
| Percentage of lung occupied by emphysema (median (IQR)) | 10.1 (6.9–12.6) | 11.9 (7.7–13.8) | |
| Percentage of lung occupied by normal parenchyma (median (IQR)) | 68.2 (62.7–72.6) | 66.4 (62.8–71.1) |