Table 1.

PC-NTDs targeted by the WHO 2021–2030 roadmap

Name of the NTD	Level of targeted control	Drugs of choice for MDA	Recommended target group for MDA
Lymphatic filariasis	Elimination as a PH problem	Albendazole, diethylcarbamazine, ivermectin	Entire community in endemic areas
Onchocerciasis	Elimination (interruption of transmission)	Ivermectin	Entire community in endemic areas
Schistosomiasis	Elimination as a PH problem	Praziquantel	At-risk groups: mainly school age children, also recommended for preschool age children and adults in high-risk occupations In highly endemic areas: entire community
Soil-transmitted helminthiases	Elimination as a PH problem	Albendazole/mebendazole (intestinal parasites and hookworms) and ivermectin (if Strongyloides present or high prevalence Trichuris)	At-risk groups: mainly school age children, also recommended for preschool age children, women of reproductive age and adults in high-risk occupations
Trachoma	Elimination as a PH problem	Azithromycin, tetracycline eye ointment	Entire community in endemic areas
Foodborne trematodiases	Intensified control	Triclabendazole (fasciola), praziquantel (others)	Entire community in highly endemic areas
Leprosy	Elimination (interruption of transmission)	Rifampicin	Contacts of confirmed cases (postexposure prophylaxis)
Scabies	Intensified control	Ivermectin	Entire community in highly endemic areas
Taeniasis and cysticercosis	Intensified control	Praziquantel, niclosamide, albendazole	Entire community in endemic areas
Yaws	Eradication	Azithromycin	Entire community in endemic areas

MDA, mass drug administration; NTDs, neglected tropical diseases ; PC, preventive chemotherapy; PH, public health.