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. 2024 Mar 14;11(1):e001959. doi: 10.1136/bmjresp-2023-001959

Table 2. Matched and adjusted HRs of the investigated diagnoses (E11-J32).

Per 10 000 person years Events Incidence rate (95% CI) per 10 000 person years Matched HR (95% CI) Adjusted HR (95% CI)
Diabetes mellitus (E11–14)
 No asthma 36.68 77 2.10 (1.66 to 2.62) 1 1
 Asthma 20.47 77 3.76 (2.97 to 4.70) 1.62 (1.13 to2.34) 2.40(1.45 to3.95) *
Transient cerebral events (G45)
 No asthma 36.37 118 3.24 (2.69 to 3.89) 1 1
 Asthma 20.42 77 3.77 (2.98 to 4.71) 1.30 (0.92 to 1.84) 1.35 (0.93 to 1.96)
Sleep apnoea (G47.3)
 No asthma 34.20 67 1.96 (1.52 to 2.49) 1 1
 Asthma 18.85 79 4.19 (3.32 to 5.22) 2.21 (1.53 to3.22) 2.07 (1.32 to3.23) *
Senile cataract (H25)
 No asthma 34.89 406 11.64 (10.53 to 12.83) 1 1
 Asthma 19.17 319 16.64 (14.87 to 18.57) 1.69 (1.39 to2.04) 1.65 (1.35 to 2.03)
Hearing loss (H90)
 No asthma 35.90 189 5.27 (4.54 to 6.07) 1 1
 Asthma 20.08 129 6.43 (5.35 to 7.64) 1.26 (0.96 to 1.64) 1.38 (1.01 to 1.88) *
Hypertensive diseases (I10)
 No asthma 36.03 168 4.66 (3.98 to 5.42) 1 1
 Asthma 20.38 90 4.42 (3.55 to 5.43) 1.10 (0.82 to 1.48) 1.18 (0.86 to 1.62)
Ischaemic heart diseases (I20, I21, I25)
 No asthma 34.43 359 10.43 (9.38 to 11.56) 1 1
 Asthma 19.19 240 12.50 (10.97 to 14.19) 1.35 (1.11 to1.64) 1.28 (1.02 to 1.61) *
Atrial fibrillation and flutter (I48), heart failure (I50)
 No asthma 35.59 268 7.53 (6.66 to 8.49) 1 1
 Asthma 19.94 198 9.93 (8.60 to 11.41) 1.43 (1.14 to1.79) 1.35 (1.05 to 1.75) *
Cerebral infarction (I63)
 No asthma 36.31 134 3.69 (3.09 to 4.37) 1 1
 Asthma 20.40 110 5.39 (4.43 to 6.50) 1.64 (1.20 to2.23) 1.65 (1.15 to 2.35) *
Varicose veins of lower extremities (I83)
 No asthma 36.00 107 2.97 (2.44 to 3.59) 1 1
 Asthma 20.16 79 3.92 (3.10 to 4.88) 1.44(1.04to2.01) 1.43 (1.01 to 2.03)
Acute rhinosinusitis (J01)
 No asthma 36.97 17 0.46 (0.27 to 0.74) 1 1
 Asthma 20.36 54 2.65 (1.99 to 3.46) 4.02 (2.26 to7.17) 4.26 (2.30 to 8.33)
Pneumonia (J15, J18)
 No asthma 36.12 230 6.37 (5.57 to 7.25) 1 1
 Asthma 19.60 255 13.00 (11.46 to 14.71) 2.52 (2.00 to3.17) 2.29 (1.79 to 2.93)
Allergic rhinitis (J30)
 No asthma 36.96 18 0.49 (0.29 to 0.77) 1 1
 Asthma 20.76 22 1.06 (0.66 to 1.60) 1.61 (0.82 to 3.15) 2.27 (1.18 to 4.35) *
Chronic rhinosinusitis (J32)
 No asthma 36.58 55 1.50 (1.13 to 1.96) 1 1
 Asthma 20.49 53 2.59 (1.94 to 3.38) 1.83 (1.20 to2.81) 1.82 (1.15 to 2.87)

Adjusted Cox’s multivariate proportional hazards models.

*

Matched for gender, age and area of residence and adjusted for pack- years and body mass index.

Matched for gender, age and area of residence and adjusted for pack- years.