Table 3. Matched and adjusted HRs of the investigated diagnoses (J33-R06).
| Per 10 000 person years | Events | Incidence rate (95% CI) per 10 000 person years | Matched HR (95% CI) | Adjusted HR (95% CI) | |
| Chronic rhinosinusitis with nasal polyps (J33) | |||||
| No asthma | 36.87 | 30 | 0.81 (0.55 to 1.16) | 1 | 1 |
| Asthma | 20.26 | 70 | 3.45 (2.69 to 4.36) | 4.08 (2.51 to6.63) | 4.28 (2.47 to 7.41) * |
| Vocal cord dysfunction (J38.3, J385–J38.7, J39.3, J39.8, J39.9) | |||||
| No asthma | 37.07 | 8 | 0.22 (0.09 to 0.43) | 1 | 1 |
| Asthma | 20.86 | 20 | 0.96 (0.59 to 1.48) | 4.69 (1.85 to11.85) | 4.60 (2.00 to 10.57) * |
| Other chronic obstructive pulmonary disease (J44) | |||||
| No asthma | 36.88 | 52 | 1.41 (1.05 to 1.85) | 1 | 1 |
| Asthma | 19.81 | 160 | 8.08 (6.88 to 9.43) | 7.93 (5.24 to12.0) | 10.62 (5.14 to21.96) † |
| Bronchiectasis (J47) | |||||
| No asthma | 35.66 | 192 | 5.38 (4.65 to 6.20) | 1 | 1 |
| Asthma | 19.86 | 153 | 7.71 (6.53 to 9.03) | 1.58 (1.23 to2.03) | 1.53 (1.06 to 2.22) * |
| Gastro-oesophageal disease (K21) | |||||
| No asthma | 36.6 | 77 | 2.10 (1.66 to 2.63) | 1 | 1 |
| Asthma | 20.27 | 86 | 4.24 (3.39 to 5.24) | 1.79 (1.26 to2.54) | 2.05 (1.40 to 2.99)† |
| Inguinal hernia (K40) | |||||
| No asthma | 36.12 | 116 | 3.21 (2.65 to 3.85) | 1 | 1 |
| Asthma | 20.34 | 72 | 3.54 (2.77 to4.46) | 1.18 (0.85 to1.66) | 1.01 (0.70 to 1.47) † |
| Cholelithiasis (K80) | |||||
| No asthma | 36.12 | 131 | 3.63 (3.03 to 4.30) | 1 | 1 |
| Asthma | 20.13 | 93 | 4.62 (3.73 to 5.66) | 1.33 (0.98 to 1.81) | 1.39 (0.99 to 1.96) * |
| Diverticular disease of intestine (K57) | |||||
| No asthma | 36.36 | 131 | 3.60 (3.01 to 4.28) | 1 | 1 |
| Asthma | 20.27 | 102 | 5.03 (4.10 to 6.11) | 1.29 (0.96 to 1.74) | 1.34 (1.02 to 1.76) * |
| Atopic dermatitis (L20) | |||||
| No asthma | 36.88 | 33 | 0.89 (0.62 to 1.26) | 1 | 1 |
| Asthma | 20.55 | 58 | 2.82 (2.14 to 3.65) | 3.24 (1.98 to5.31) | 4.01 (2.32 to6.94) † |
| Arthrosis of hip or knee (M16,M17) | |||||
| No asthma | 34.44 | 315 | 9.15 (8.16 to 10.22) | 1 | 1 |
| Asthma | 19.24 | 215 | 11.17 (9.73 to 12.77) | 1.34 (1.09 to1.64) | 1.31 (1.03 to 1.65) * |
| Intervertebral disc disorders or dorsalgia (M51, M54) | |||||
| No asthma | 35.19 | 241 | 6.85 (6.01 to 7.77) | 1 | 1 |
| Asthma | 19.13 | 222 | 11.60 (10.13 to 13.24) | 1.74 (1.41 to2.14) | 1.79 (1.41 to2.27) * |
| Shoulder lesions and other soft-tissue disorders (M75, M79) | |||||
| No asthma | 35.44 | 222 | 6.26 (5.47 to 7.14) | 1 | 1 |
| Asthma | 19.34 | 198 | 10.24 (8.86 to 11.77) | 1.78 (1.42 to2.23) | 1.72 (1.34 to2.21) * |
| Other disorders of urinary system (N39) | |||||
| No asthma | 36.21 | 132 | 3.65 (3.05 to 4.32) | 1 | 1 |
| Asthma | 20.27 | 103 | 5.08 (4.15 to 6.16) | 1.60 (1.18 to2.18) | 1.61 (1.17 to2.23)‡ |
| Hyperplasia of prostate (N40) | |||||
| No asthma | 36.05 | 139 | 3.86 (3.24 to 3.39) | 1 | 1 |
| Asthma | 20.32 | 86 | 4.23 (3.39 to 5.23) | 1.30 (0.94 to 1.82) | 1.26 (0.87 to 1.84) † |
| Breathing dysfunction (R06.1–R06.5) | |||||
| No asthma | 36.88 | 25 | 0.68 (0.44 to 1.00) | 1 | 1 |
| Asthma | 20.65 | 33 | 1.60 (1.10 to 2.24) | 2.36 (1.34 to4.15) | 2.31 (1.35 to 3.96) † |
Adjusted Cox’s multivariate proportional hazards models.
*
Matched for gender, age and area of residence and adjusted for pack- years and body mass index.
†
Matched for gender, age and area of residence and adjusted for pack- years.
‡
Matched for gender, age and area of residence and adjusted for body mass index. Bold values denote statistical significance at the pp<0.05 level.