Figure 21.

VSC-induced chemical reactivity of an alcoholysis reaction, described by an open quantum mechanical model. (a) The reactants phenyl isocyanate (PHI) and cyclohexanol (CHol) were combined in tetrahydrofuran (THF) to form cyclohexyl carbanilate (CC). (b) A solution was contained between two CaF₂ windows that were either transparent (for control measurements) or coated with Au/SiO₂ (for cavity-coupled experiments). (c) Reaction suppression was observed when the cavity was tuned to prominent vibrational modes (CH and NCO modes) compared to the control experimental results, where reaction rate constants were extracted from linear fitting. (d) Cavity-detuning-dependent vibrational population redistribution predicted by the cavity quantum mechanical model. Reprinted with permission from ref (125). Copyright 2023 American Association for the Advancement of Science.