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. 2024 Feb 29;14:1327046. doi: 10.3389/fonc.2024.1327046

Table 4.

Diagnostic Performance of variables for predicting EPE.

parameters Cut off value AUC 95% CI Sensitivity Specificity P values
APT 3.650 0.752 0.649-0.855 76% 89.4% <0.001
ADC 0.97 0.665 0.557-0.773 80% 59.6% 0.005
Tumor size 17.30 0.700 0.597-0.803 54% 78.9% 0.001
LCC 10.78 0.756 0.661-0.851 72% 66% <0.001
Combined
Model I
/ 0.803 0.718-0.888 74% 72.3% <0.001
Combined
Model II
/ 0.845 0.766-0.924 82% 75.5% <0.001
Combined
Model III
/ 0.869 0.793-0.940 84% 80.9% <0.001

APT, amide proton transfer; ADC, apparent diffusion coefficient; LCC, length of capsular contact; EPE, Extraprostatic extension; Combined Model I, LCC + tumor size + ADC; Combined Model II, LCC + tumor size + APT; Combined Model III, LCC + tumor size + ADC + APT.

Bold font represents statistical significance.