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. 2024 Feb 29;12:1356458. doi: 10.3389/fchem.2024.1356458

TABLE 2.

Partial results of KEGG pathway enrichment analysis.

ID Description pvalue Count geneID
hsa05418 Fluid shear stress and atherosclerosis 6.22E-23 28 BCL2/NOS3/AKT1/TNF/MAPK8/HMOX1/ICAM1/SELE/VCAM1/GSTM1/GSTM2/KDR/VEGFA/FOS/MMP2/MMP9/TP53/CAV1/IL1B/CCL2/PLAT/THBD/IFNG/IL1A/NCF1/NFE2L2/PIK3CA/TRPV4
hsa05417 Lipid and atherosclerosis 1.40E-16 27 BCL2/CASP3/PRKCA/PPARG/NOS3/AKT1/TNF/MAPK8/MMP1/CYP1A1/ICAM1/SELE/VCAM1/MMP3/FOS/MMP9/MAPK1/IL6/TP53/IL1B/CCL2/CXCL8/NCF1/NFE2L2/CD40LG/PIK3CA/LDLR
hsa04933 AGE-RAGE signaling pathway in diabetic complications 2.92E-27 28 BCL2/CASP3/PRKCA/TGFB1/NOS3/AKT1/TNF/MAPK8/STAT1/ICAM1/SELE/VCAM1/VEGFA/CCND1/MMP2/MAPK1/IL6/F3/IL1B/CCL2/CXCL8/THBD/SERPINE1/COL1A1/IL1A/COL3A1/PIK3CA/CDKN1B
hsa04066 HIF-1 signaling pathway 6.20E-17 21 BCL2/PRKCA/NOS2/NOS3/AKT1/HMOX1/INSR/EGFR/VEGFA/CDKN1A/MAPK1/EGF/IL6/HIF1A/SERPINE1/IFNG/MTOR/PIK3CA/CDKN1B/VHL/FLT1
hsa04020 Calcium signaling pathway 1.37E-12 24 PRKACA/DRD1/HTR2A/ADRA1A/ADRA1B/ADRB2/PRKCA/NOS2/F2R/NOS3/KDR/MET/ADRA1D/ADRB1/NGF/EGFR/VEGFA/EGF/AVPR1A/TBXA2R/RET/EDNRB/CACNA1B/FLT1