Schawkat 2019.

Study characteristics
Methods	Study design: parallel‐group randomized controlled trial, single center Study period: June 2017 to June 2018 Number randomized: NR Unit of randomization: individual Exclusions after randomization: NR Losses to follow‐up: none Number analyzed: 49 participants (50 eyes) in total; 26 for log‐roll group and 24 for lie‐flat group Unit of analysis: eyes Length of follow‐up: planned: NR; actual: 6 weeks How were missing data handled?: NR Power calculation: sample size: 23 per cohort; power: 90%
Participants	Country: Switzerland Setting: Eye Clinic, Cantonal Hospital Sankt Gallen Age: overall: median age 69; range 43 to 90 years; group: NR Gender, n (%): overall: 36 (72%) male and 14 (28%) female; group: NR Race/ ethnicity, n (%): NR Quadrants of retinal detached, n (%), (1 : 2 : 3: 4): overall: 2 (4%) : 23 (46%) : 17 (34%) : 8 (16%); group: NR PFCL, n (%): overall: 25 (50%) yes and 25 (50%) no; group: NR Tamponade, n (%): overall: 44 (88%) SF6 and 6 (12%) C3F8; group: NR Inclusion criteria: Patients who presented with a macula‐off retinal detachment Exclusion criteria: Patients suffering from other forms of retinal detachment such as exudative or tractional Patients with proliferative vitreoretinopathy, retinal reattachments, and patients who needed a primary oil fill
Interventions	Intervention 1 (log‐roll): "30 minutes face to temporal followed by 30 minutes face down before moving into the end position (final position taken according to location of retinal break). Final position was maintained for about 7 days postoperatively." Intervention 2 (lie‐flat): "lie flat on back for at least 6 hours before moving into the end position (final position taken according to location of retinal break). Final position was maintained for about 7 days postoperatively." Surgical details: "A standard core and peripheral 3‐port PPV (23‐ gauge)was performed in all patients. Surgery was done with general anesthesia. After the vitrectomy and separation of the posterior hyaloids using the suction method, retinal reattachment was achieved directly through fluid–air exchange with subretinal fluid drainage via main peripheral breaks or through perfluorooctane liquid followed by fluid–air exchange. Adjuvant posterior retinotomies were not performed. Retinopexy was done using endolaser or transconjunctival cryocoagulation. 12% Perfluoropropane (C3F8) or 20% sulfur hexafluoride (SF6) gas tamponade was applied after the surgery. Rhegmatogenous retinal detachment characteristics determined the selection of intraocular tamponade. Nevertheless, in principle, an injection of SF6 gas was employed for retinal breaks within the upper 240 retinal degrees, whereas an injection of C3F8 gas was used when inferior retinal tears appeared and for patients with a low‐compliance posture. For phakic eyes, PPV and phacoemulsification were conducted in a single procedure. Postoperatively, patients were asked to perform initial posturing according to randomization before moving into the end position."
Outcomes	Primary outcome(s): type of posture influenced the occurrence of postoperative macular shift postoperation Secondary outcome(s): use of heavy liquid, type of gas used, number of quadrants detached, and age of the patient postoperation Adverse outcome(s): NR
Notes	Funding sources: no funding or sponsorship was received for this study. Disclosures of interest: Josef Guber, Megir Schawkat, Christophe Valmaggia, Corina Lang, Hendrik Scholl, Steven Harsum, and Ivo Guber have nothing to declare. Trial registry: NR Publication language: English

^aApproximate Snellen equivalent for 3/60 is 20/400; for 6/36 is 20/125, and for 6/24 is 20/80.
^bNumbers are mutually exclusive.
^cQuadrants of the eye, i.e. supertemporal, superonasal, inferotemporal, inferonasal.

ACIOL: anterior chamber intraocular lens
BCVA: best‐corrected visual acuity
C2F6: hexafluoroethane
C3F8: perfluoropropane
ETDRS: Early Treatment Diabetic Retinopathy Study
HM: hand motion
IOP: intraocular pressure
IQR: interquartile range
logMAR: logarithm of the Minimum Angle of Resolution
NA: not applicable
NR: not reported
NEI‐VFQ 25: 25‐item version of the 41‐item National Eye Institute Visual Function Questionnaire
PCIOL: posterior chamber intraocular lens
PFCL: perfluorocarbon liquid
PPV: pars plana vitrectomy
PVR: proliferative vitreoretinopathy
PVR B: inner retinal wrinkling, retinal stiffness, rolled retinal break edges, vitreous stiffness
PVR C: full‐thickness retinal folds or subretinal strands
RCT: randomized controlled trial
RD: retinal detachment
RRD: rhegmatogenous retinal detachment
SD: standard deviation
SD‐OCT: spectral domain optical coherence tomography
SF6: sulfur hexafluoride gas