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. 2023 Dec 21;102:skad417. doi: 10.1093/jas/skad417

Table 3.

MIC50, MIC90, range and percent of P. multocida and M. haemolytica isolates collected from high-risk beef stocker calves prior to and 14 d after administration of saline susceptible to 12 antimicrobials at the time of arrival processing

Pasteurella multocida Mannheimia haemolytica
Antimicrobial Sampling occasion MIC50 (μg/mL) MIC90 (μg/mL) Range (μg/mL) % Susceptible MIC50 (μg/mL) MIC90 (μg/mL) Range (μg/mL) % Susceptible
Ampicillin 1 ≤0.25 ≤0.25 ≤0.25 N/A N/A N/A N/A N/A
2 ≤0.25 ≤0.25 ≤0.25 N/A ≤0.25 0.5 ≤0.25 to 0.5 N/A
Ceftiofur 1 ≤0.25 ≤0.25 ≤0.25 100 N/A N/A N/A N/A
2 ≤0.25 ≤0.25 ≤0.25 100 ≤0.25 2 ≤0.25 to 2 100
Chlortetracycline 1 ≤0.5 2 ≤0.5 to 2 N/A N/A N/A N/A N/A
2 ≤0.5 2 ≤0.5 to 8 N/A >8 >8 0.5 to >8 N/A
Danofloxacin 1 ≤0.125 ≤0.125 ≤0.125 100 N/A N/A N/A N/A
2 ≤0.125 ≤0.125 ≤0.125 100 ≤0.125 >1 ≤0.125 to >1 86
Enrofloxacin 1 ≤0.125 ≤0.125 ≤0.125 100 N/A N/A N/A N/A
2 ≤0.125 ≤0.125 ≤0.125 100 ≤0.125 >2 ≤0.125 to >2 86
Florfenicol 1 0.5 1 0.25 to 1 100 N/A N/A N/A N/A
2 0.5 1 0.25 to 1 100 1 >8 ≤0.25 to >8 86
Oxytetracycline 1 ≤0.5 4 ≤0.5 to 8 93 N/A N/A N/A N/A
2 ≤0.5 8 ≤0.5 to >8 80 >8 >8 0.5 to >8 46
Penicillin 1  ≤ 0.125 0.25  ≤ 0.125 to 0.25 100 N/A N/A N/A N/A
2  ≤ 0.125 0.25  ≤ 0.125 to 0.25 100 0.5 1 ≤0.125 to 1 50
Spectinomycin 1 16 32 8 to >64 93 N/A N/A N/A N/A
2 16 >64 8 to >64 83 32 >64 ≤8 to >64 86
Tilmicosin 1 ≤4 32 ≤4 to >64 93 N/A N/A N/A N/A
2 ≤4 64 ≤4 to >64 86 8 >64 8 to >64 79
Tulathromycin 1 ≤1 32 1 to >64 93 N/A N/A N/A N/A
2 ≤1 >64 1 to >64 86 8 >64 ≤1 to >64 86
Tylosin 1 16 >32 8 to >32 N/A N/A N/A N/A N/A
2 16 >32 16 to >32 N/A >32 >32 8 to >32 N/A

N/A—breakpoints not available or too few isolates to summarize.