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. 2023 Dec 21;102:skad417. doi: 10.1093/jas/skad417

Table 4.

MIC50, MIC90, range and percent of P. multocida isolates collected from high-risk beef stocker calves prior to and 14 d after administration of tulathromycin susceptible to 12 antimicrobials at the time of arrival processing

Pasteurella multocida
Antimicrobial Sampling occasion MIC50 (μg/mL) MIC90 (μg/mL) Range (μg/mL) % Susceptible
Ampicillin 1 ≤0.25 ≤0.25 ≤0.25 N/A
2 ≤0.25 ≤0.25 ≤0.25 N/A
Ceftiofur 1 ≤0.25 ≤0.25 ≤0.25 100
2 ≤0.25 ≤0.25 ≤0.25 100
Chlortetracycline 1 ≤0.5 >8 ≤0.5 to >8 N/A
2 2 >8 ≤0.5 to 8 N/A
Danofloxacin 1 ≤0.125 ≤0.125 ≤0.125 100
2 ≤0.125 ≤0.125 ≤0.125 100
Enrofloxacin 1 ≤0.125 ≤0.25 ≤0.125 to 0.25 100
2 ≤0.125 ≤0.125 ≤0.125 100
Florfenicol 1 0.5 1 ≤0.25 to 1 100
2 1 1 ≤0.25 to 1 100
Oxytetracycline 1 ≤0.5 >8 ≤0.5 to >8 90
2 1 >8 ≤0.5 to >8 60
Penicillin 1  ≤ 0.125 0.25  ≤ 0.125 to 0.25 100
2 0.25 0.5  ≤ 0.125 to 0.5 80
Spectinomycin 1 16 >64 8 to >64 90
2 16 >64 8 to >64 60
Tilmicosin 1 ≤4 >64 ≤4 to >64 90
2 8 >64 ≤4 to >64 60
Tulathromycin 1 ≤1 >64 ≤1 to >64 90
2 4 >64 ≤1 to >64 60
Tylosin 1 16 >32 8 to >32 N/A
2 16 >32 16 to >32 N/A

N/A—breakpoints not available or too few isolates to summarize.