Table 2. Procedural data.

Variable	ACURATE (n=251)	EVOLUT (n=584)	p-value	ACURATE (n=234)	EVOLUT (n=234)	p-value
Prosthesis size			<0.001			<0.001
Small (23 mm)	195 (77.7)	291 (49.8)		180 (76.9)	108 (46.2)
Medium (25, 26 mm)	47 (18.7)	234 (40.1)		45 (19.2)	105 (44.9)
Large (27, 29, 34 mm)	9 (3.6)	59 (10.1)		9 (3.8)	21 (9.0)
Cover index, %	8.7 [8.7; 17.4]	17.4 [11.5; 19.2]	<0.001	8.7 [8.7; 17.4]	17.4 [13.8; 19.2]	<0.001
Early-generation device	132 (52.6)	569 (97.4)	<0.001
Procedural duration, min	53 [37;80]; 236	74 [55; 105]; 544	<0.001	52 [36; 80]	74 [56; 100]	<0.001
Fluoroscopy time, min	12.4 [9.0; 20.3]; 234	18 [12.6; 27.5]; 541	<0.001	12.3 [9.0; 19.5]	18.1 [13.3; 27.1]	<0.001
Contrast agent, ml	60 [25; 98]; 245	95 [50; 146]; 571	<0.001	60 [22; 95]	96 [50; 140]	<0.001
Predilatation	111 (44.4)	42 (7.2)	0.037	102 (43.6)	19 (8.1)	<0.001
Post-dilatation	144 (57.4)	289 (49.5)	0.195	136 (58.1)	115 (49.1)	0.064
Attempted BVF	9 (3.6)	12 (2.1)	0.067	9 (3.8)	5 (2.1)	0.417
BVF timing at predilatation	8/9 (88.9)	5/12 (41.7)	0.171	8/9 (88.9)	1/5 (20.0)	0.023
BVF successful	7/9 (77.8)	12/12 (100)	0.119	7/9 (77.8)	5/5 (100)	0.505
Haemodynamic compromise after BVF	4/9 (44.4)	1/12 (8.3)	<0.001	4/9 (44.4)	1/5 (20.0)	0.580
Cerebral protection	19 (7.6)	186 (31.9)	<0.001	18 (7.7)	70 (29.9)	<0.001
Commissural alignment	98 (39.0)	15 (2.6)	0.111	91 (38.9)	8 (3.4)	<0.001
Coronary protection	49 (19.5)	88 (15.1)	<0.001	40 (17.1)	44 (18.8)	0.186
Implantation depth, mm	2.5 [1.0; 4.5]; 240	4.7 [2.7; 6.4]; 468	<0.001	2.0 [1.0; 4.2]	4.0 [3.0; 6.0]	<0.001
Values denote n (%), n/N (%), median [IQR]. ACURATE: ACURATE neo/neo2 group; BVF: bioprosthetic valve fracturing; EVOLUT: Evolut R/PRO/PRO+ group; IQR: interquartile range