| Mean gradient post-intervention, mmHg |
13.0 [9.0; 19.0]; 249 |
13.0 [9.0; 18.0]; 561 |
0.376 |
13.0 [9.0; 19.0] |
12.0 [9.0; 16.0] |
0.193 |
| EOA post-intervention, cm2
|
1.5 [1.3; 1.7]; 187 |
1.5 [1.3; 1.9]; 250 |
0.021 |
1.5 [1.3; 1.7] |
1.5 [1.4; 2.0] |
0.022 |
| Severe PPM |
30/181 (16.6) |
35/249 (14.1) |
0.472 |
28 (16.6) |
10 (9.8) |
0.149 |
| AR ≥moderate |
6/249 (2.4) |
17/574 (3.0) |
0.659 |
6 (2.6) |
4 (1.7) |
0.532 |
| Technical success (VARC-3) |
229 (91.2) |
521 (89.2) |
0.375 |
217 (92.7) |
208 (88.9) |
0.200 |
| Device success (VARC-3) |
171 (68.1) |
402 (68.8) |
0.840 |
163 (69.7) |
173 (73.9) |
0.355 |
| Coronary occlusion requiring PCI |
13 (5.2) |
24 (4.1) |
0.491 |
9 (3.8) |
11 (4.7) |
0.820 |
| Myocardial infarction |
1 (0.4) |
4 (0.7) |
0.623 |
0 |
2 (0.9) |
0.499 |
| Annular rupture |
0 |
1 (0.2) |
0.512 |
0 |
1 (0.4) |
>0.99 |
| Conversion to sternotomy |
1 (0.4) |
2 (0.3) |
0.901 |
1 (0.4) |
0 |
>0.99 |
| Multiple valve implantation |
4 (1.6) |
8 (1.4) |
0.803 |
4 (1.7) |
4 (1.7) |
>0.99 |
| Malpositioning |
6 (3.1) |
18 (3.1) |
0.936 |
7 (3.0) |
5 (2.1) |
0.771 |
| Major vascular complication |
14 (5.6) |
36 (6.2) |
0.743 |
12 (5.1) |
11 (4.7) |
>0.99 |
| Type 3-4 bleeding |
10 (4.2) |
30 (5.1) |
0.474 |
8 (3.4) |
13 (5.6) |
0.372 |
| Any stroke |
4 (1.6) |
11 (1.9) |
0.770 |
4 (1.7) |
6 (2.6) |
0.751 |
| Acute kidney injury stage 3-4 |
5 (2.0) |
23 (4.0) |
0.152 |
4 (1.7) |
6 (2.6) |
0.751 |
| Pacemaker implantation |
2 (0.8) |
17 (2.9) |
0.060 |
2 (0.9) |
6 (2.6) |
0.285 |
| Values denote n (%), n/N (%), or median [IQR]. ACURATE: ACURATE neo/neo2 group; AR: aortic regurgitation; EOA: effective orifice area; EVOLUT: Evolut R/PRO/PRO+ group; IQR: interquartile range; PCI: percutaneous coronary intervention; PPM: prosthesis-patient mismatch; VARC: Valvular Academic Research Consortium |
