Table 3. CytoHubba nodes' score of the top 10 nodes obtained from local topological algorithms.

Ranks	MCC protein	MCC score	MNC protein	MNC score	DMNC protein	DMNC score	Degree protein	Degree score
1	APP	127444	APP	37	APOA1	0.83	APP	37
2	APOE	121974	APOE	23	APOB	0.83	APOE	23
3	CLU	121104	PSEN1	18	APOA2	0.83	PSEN1	18
4	APOA1	120960	CLU	16	APOC2	0.83	CLU	16
5	APOB	120960	NCSTN	14	APOC3	0.83	BACE1	15
6	APOA2	120960	BACE1	14	LRP1	0.81	NCSTN	14
7	APOC2	120960	GSK3B	11	LRP8	0.81	GSK3B	11
8	APOC3	120960	APOA1	10	APOC1	0.81	APOA1	10
9	LRP1	40320	APOB	10	APH1A	0.76	APOB	10
10	LRP8	40320	APOA2	10	PSENEN	0.76	APOA2	10