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Categories for REP derivation method.
| High |
| Modeled REP based on parallelism |
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| Medium |
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| Modeled REP with no evaluation of parallelism |
| REP calculated by linear interpolation |
| Partial least squared analysis |
| Linear extrapolation +average response ratios |
| Dose-response graphs |
| ED50, EC50 or LD50 ratios |
| Curve fitting |
| Graphical comparison of dose response curves |
| Promotion index ratio |
|
|
| Low |
|
|
| Dose estimates, crude estimates |
|
|
| QSAR |
|
|
| (Or other model) |
