TABLE 3.
US cohort characteristics.
| Variable | Kidney function | ||
|---|---|---|---|
| EF | DGF | p-value b | |
| N = 44,731 (73%) a | N = 26,674 (27%) a | ||
| Donor age (years) | 37 (25,50) | 42 (30,53) | <0.001 |
| Donor sex | 0.034 | ||
| Female | 18,030 (40%) | 6,563 (39%) | |
| Male | 26,701 (60%) | 10,111 (61%) | |
| Kidney Donor Profile Index | 43.0 (22.0, 66.0) | 53.0 (33.0, 73.0) | <0.001 |
| Cold ischemia time (hours) | 15.6 (10.4, 21.5) | 18.0 (12.4, 24.2) | <0.001 |
| HLA mismatch | 4.0 (3.0, 5.0) | 4.0 (4.0, 5.0) | <0.001 |
| Recipient age at transplant (years) | 54 (42,63) | 56 (46,64) | <0.001 |
| Recipient sex | <0.001 | ||
| Female | 18,728 (42%) | 5,431 (33%) | |
| Male | 26,003 (58%) | 11,243 (67%) | |
| Recipient diabetes | 15,152 (34%) | 7,252 (44%) | <0.001 |
| Recipient previous kidney transplant | 5,883 (13%) | 2,233 (13%) | 0.442 |
| Follow up time (months) | 35.2 (17.7,53.2) | 29.4 (12.3,48.2) | <0.001 |
| Donor cause of death | <0.001 | ||
| Anoxia | 17,378 (39%) | 7,064 (42%) | |
| Cerebrovascular/stroke | 11,443 (26%) | 5,179 (31%) | |
| Head trauma | 14,648 (33%) | 3,998 (24%) | |
| CNS Tumor | 207 (0%) | 62 (0%) | |
| Other | 1,055 (2%) | 371 (2%) | |
| Donor serum creatinine | 0.9 (0.7–1.3) | 1.2 (0.8–2.2) | <0.001 |
| Donor ethnicity | <0.001 | ||
| Asian | 1,114 (2%) | 519 (3%) | |
| Black | 7,255 (16%) | 2,639 (16%) | |
| Multi | 175 (0%) | 85 (1%) | |
| Native | 284 (1%) | 89 (1%) | |
| Pacific | 157 (0%) | 62 (0%) | |
| White | 35,756 (80%) | 13,280 (80%) | |
| Recipient ethnicity | <0.001 | ||
| Asian | 3,318 (7%) | 1,239 (7%) | |
| Black | 15,399 (34%) | 6,653 (40%) | |
| Multi | 337 (1%) | 115 (1%) | |
| Native | 436 (1%) | 205 (1%) | |
| Pacific | 236 (1%) | 83 (0%) | |
| White | 25,005 (56%) | 8,379 (50%) | |
a
Median (25%, 75%); n (%).
b
Mann-Whitney test for continuous, Chi-square for categorical variables EF, early function; DGF, delayed graft function; HLA, human leukocyte antigens.