Table 4. Direct infusion mass spectrometry serum biogenic amines (μM) from 14 lean (L-MAINT) and 16 obese (O-MAINT) cats during weight maintenance and after 10-week energy restriction (O-RESTRICT).

Metabolite (μM)	L-MAINT (n = 14)	O-MAINT (n = 16)	O-RESTRICT (n = 16)	P-Value
				L-MAINT: O-MAINT	L-MAINT: O-RESTRICT	O-MAINT: O-RESTRICT
Acetylornithine	6.02 (4.06–9.68)	6.85 (5.46–9.33)	6.30 (4.33–9.85)	0.10	0.80	0.07
Asymmetric dimethylarginine	2.49 ± 0.15	2.58 ± 0.13	2.61 ± 0.12	0.62	0.52	0.86
Alpha-Aminoadipic acid	2.13 ± 0.18	1.98 ± 0.07	2.10 ± 0.11	0.43	0.90	0.32
Carnosine	46.73 ± 3.48	43.12 ± 3.26	42.69 ± 2.79	0.46	0.37	0.86
Creatinine	128.72 ± 6.92AB	113.68 ± 5.40 A	133.63 ± 7.15 B	0.09	0.62	0.02
Histamine	0.046 (0.04–0.07) A	0.052 (0.04–0.1) B	0.050 (0.04–0.1)AB	0.04	0.38	0.27
Kynurenine	8.46 (4.51–15.20)	8.27 (4.85–23.90)	8.36 (6.53–14.60)	0.76	0.69	0.97
Methioninesulfoxide	4.99 (2.24–16.10)	8.10 (3.33–14.80)	6.33 (2.14–23.50)	0.17	0.53	0.83
Trans-hydroxyproline	30.67 ± 3.83	36.92 ± 3.38	36.23 ± 3.20	0.23	0.27	0.81
Putrescine	1.07 ± 0.08	1.17 ± 0.10	1.09 ± 0.092	0.48	0.91	0.47
Serotonin	12.80 ± 0.63	13.05 ± 0.97	13.07 ± 0.95	0.83	0.82	0.99
Spermidine	0.6 (0.42–1.25)	0.64 (0.39–0,99)	0.51 (0.36–1.02)	0.37	0.13	0.26
Spermine	0.28 ± 0.02	0.30 ± 0.03	0.33 ± 0.04	0.76	0.42	0.35
Taurine	226.50 (129.0–302.0)	222.00 (120.0–293.0)	208.50 (142.0–297.0)	0.66	0.94	0.97
Total Biogenic Amines	459.32 ± 92.98	445.66 ± 63.88	463.85 ± 62.77	0.64	0.88	0.26

Normally distributed data expressed as mean ± SE

Non-parametric data expressed as median (min-max).

Superscript capital letters (A, B) denote significant differences between groups with different letters where a p-value <0.05 is considered significant

No superscript letters in a row indicates no significant differences between groups for the measured parameter