Table 5. Direct infusion mass spectrometry serum phosphatidylcholine diacyls (PC aa) (μM) from 14 lean (L-MAINT) and 16 obese (O-MAINT) cats during weight maintenance and after 10-week energy restriction (O-RESTRICT).
| Metabolite (μM) | L-MAINT (n = 14) | O-MAINT (n = 16) | O-RESTRICT (n = 16) | P-Value | ||
|---|---|---|---|---|---|---|
| L-MAINT: O-MAINT | L-MAINT: O-RESTRICT | O-MAINT: O-RESTRICT | ||||
| PC aa C24:0 | 0.11 ± 0.01AB | 0.13 ± 0.01 A | 0.11 ± 0.01 B | 0.14 | 0.81 | 0.04 |
| PC aa C28:1 | 2.12 (1.38–2.86) | 2.16 (1.43–3.59) | 1.90 (1.30–2.75) | 0.60 | 0.36 | 0.22 |
| PC aa C30:0 | 3.61 ± 0.29 | 4.02 ± 0.30 | 3.35 ± 0.25 | 0.33 | 0.24 | 0.06 |
| PC aa C32:0 | 6.41 ± 0.36 | 6.93 ± 0.42 | 6.31 ± 0.34 | 0.21 | 0.37 | 0.85 |
| PC aa C32:1 | 7.39 ± 0.57 A | 9.38 ± 0.71 B | 7.95 ± 0.63 AB | 0.04 | 0.52 | 0.13 |
| PC aa C32:2 | 1.21 (0.50–3.98)AB | 2.16 (0.75–3.05) A | 1.11 (0.22–2.70) B | 0.06 | 0.63 | 0.007 |
| PC aa C32:3 | 0.24 ± 0.03AB | 0.26 ± 0.03 A | 0.19 ± 0.02 B | 0.61 | 0.16 | 0.049 |
| PC aa C34:1 | 111.35 ± 4.89 | 119.54 ± 6.71 | 111.23 ± 4.64 | 0.34 | 0.99 | 0.21 |
| PC aa C34:2 | 294.07 ± 22.70 | 335.75 ± 18.79 | 308.63 ± 15.81 | 0.17 | 0.60 | 0.23 |
| PC aa C34:3 | 24.49 ± 2.69 | 28.54 ± 2.27 | 23.51 ± 1.92 | 0.26 | 0.77 | 0.06 |
| PC aa C34:4 | 0.84 ± 0.10AB | 1.01 ± 0.09 A | 0.73 ± 0.08 B | 0.20 | 0.40 | 0.009 |
| PC aa C36:0 | 4.97 (3.08–7.52) | 4.49 (3.07–9.63) | 4.10 (2.66–6.63) | 0.98 | 0.11 | 0.12 |
| PC aa C36:1 | 102.50 (72.70–130.00) | 110.50 (69.20–157.00) | 96.45 (65.00–127.00) | 0.35 | 0.48 | 0.13 |
| PC aa C36:2 | 569.50 (411.00–707.00) | 631.00 (458.00–840.00) | 589.50 (409.00–808.00) | 0.05 | 0.51 | 0.16 |
| PC aa C36:3 | 148.79 ± 13.55 | 173.88 ± 11.07 | 149.67 ± 9.65 | 0.16 | 0.96 | 0.08 |
| PC aa C36:4 | 106.53 ± 5.99AB | 121.64 ± 6.78 A | 104.47 ± 5.07 B | 0.11 | 0.79 | 0.03 |
| PC aa C36:5 | 13.88 ± 1.25AB | 15.17 ± 1.03 A | 12.39 ± 0.83 B | 0.43 | 0.32 | 0.007 |
| PC aa C36:6 | 0.60 ± 0.08AB | 0.63 ± 0.06 A | 0.47 ± 0.06 B | 0.84 | 0.19 | 0.001 |
| PC aa C38:0 | 1.36 ± 0.10 | 1.16 ± 0.10 | 1.09 ± 0.09 | 0.18 | 0.06 | 0.31 |
| PC aa C38:1 | 2.05 (1.26–2.88) | 1.74 (1.07–3.14) | 1.56 (0.91–3.14) | 0.23 | 0.12 | 0.64 |
| PC aa C38:3 | 36.85 ± 1.66AB | 41.43 ± 2.64 A | 34.99 ± 2.55 B | 0.17 | 0.52 | 0.07 |
| PC aa C38:4 | 179.50 ± 12.54AB | 210.88± 14.74 A | 188.13 ± 12.36 B | 0.12 | 0.63 | 0.01 |
| PC aa C38:5 | 43.62 ± 2.52 A | 52.58 ± 3,20 B | 48.19 ± 3.20 A | 0.04 | 0.28 | 0.045 |
| PC aa C38:6 | 27.35 (18.20–53.60) | 31.80 (19.30–73.90) | 31.00 (17.10–66.80) | 0.25 | 0.15 | 0.84 |
| PC aa C40:2 | 0.79 ± 0.06 | 0.79 ± 0.06 | 0.68 ± 0.05 | 0.95 | 0.16 | 0.07 |
| PC aa C40:3 | 1.20 (0.80–1.62) | 1.27 (0.80–2.11) | 0.93 (0.65–1.76) | 0.70 | 0.14 | 0.14 |
| PC aa C40:4 | 7.87 (5.40–9.78)AB | 7 .42 (5.01–14.10) A | 6.16 (3.90–12.00) B | 0.49 | 0.07 | 0.07 |
| PC aa C40:5 | 11.69 ± 0.88 | 15.10 ± 1.43 | 14.90 ± 1.40 | 0.06 | 0.07 | 0.77 |
| PC aa C40:6 | 21.65 (9.86–59.90) | 26.50 (11.50–97.00) | 29.70 (13.80–80.00) | 0.27 | 0.09 | 0.34 |
| PC aa C42:0 | 0.06 ± 0.01 | 0.06 ± 0.01 | 0.07 ± 0.01 | 0.92 | 0.81 | 0.55 |
| PC aa C42:1 | 0.11 (0.06–0.16) | 0.10 (0.07–0.16) | 0.09 (0.03–0.16) | 0.16 | 0.07 | 0.56 |
| PC aa C42:2 | 0.45 (0.14–0.80) | 0.42 (0.27–0.73) | 0.37 (0.28–0.63) | 0.73 | 0.28 | 0.52 |
| PC aa C42:4 | 0.35 (0.15–0.45) A | 0.28 (0.20–0.59)AB | 0.26 (0.14–0.48) B | 0.34 | 0.03 | 0.11 |
| PC aa C42:5 | 0.33 (0.21–0.45) | 0.37 (0.21–0.61) | 0.30 (0.21–0.67) | 0.10 | 0.86 | 0.13 |
| PC aa C42:6 | 0.54 (0.35–0.67) | 0.58 (0.29–1.42) | 0.55 (0.24–1.75) | 0.44 | 0.92 | 0.42 |
| Total PC aa | 1723.01 (1245.25–2256.13) | 1905.78 (1443.94–2561.36) | 1725.79 (1346.93–2487.57) | 0.05 | 0.60 | 0.12 |
Normally distributed data expressed as mean ± SE
Non-parametric data expressed as median (min-max).
Superscript capital letters (A, B) denote significant differences between groups with different letters where a p-value <0.05 is considered significant
No superscript letters in a row indicates no significant differences between groups for the measured parameter