Table 6. Direct infusion mass spectrometry serum phosphatidylcholine acyl-alkyls (PC ae) (μM) from 14 lean (L-MAINT) and 16 obese (O-MAINT) cats during weight maintenance and after 10-week energy restriction (O-RESTRICT).
| Metabolite (μM) | L-MAINT (n = 14) | O-MAINT (n = 16) | O-RESTRICT (n = 16) | P-Value | ||
|---|---|---|---|---|---|---|
| L-MAINT: O-MAINT | L-MAINT: O-RESTRICT | O-MAINT: O-RESTRICT | ||||
| PC ae C30:0 | 0.40 (0.16–0.61) A | 0.34 (0.24–0.66)AB | 0.32 (0.22–0.48) B | 0.37 | 0.04 | 0.11 |
| PC ae C32:1 | 0.78 ± 0.05 | 0.80 ± 0.06 | 0.69 ± 0.04 | 0.81 | 0.18 | 0.10 |
| PC ae C32:2 | 0.25 ± 0.02 | 0.26 ± 0.02 | 0.26 ± 0.02 | 0.59 | 0.68 | 0.82 |
| PC ae C34:0 | 0.85 (0.48–2.30) | 0.68 (0.49–1.50) | 0.67 (0.45–0.95) | 0.26 | 0.05 | 0.44 |
| PC ae C34:1 | 8.39 (4.82–11.70) | 7.34 (5.14–12.50) | 7.75 (4.80–9.75) | 0.94 | 0.53 | 0.76 |
| PC ae C34:2 | 8.97 (4.95–11.80) | 7.18 (5.74–13.40) | 8.51 (5.35–12.60) | 0.20 | 0.53 | 0.13 |
| PC ae C34:3 | 2.54 (1.30–2.79) | 1.84 (1.35–3.65) | 1.93 (1.38–3.27) | 0.08 | 0.47 | 0.41 |
| PC ae C36:0 | 1.66 (0.62–4.53) | 1.29 (0.83–2.48) | 1.25 (0.75–2.56) | 0.28 | 0.09 | 0.47 |
| PC ae C36:1 | 6.65 (4.00–7.79) | 5.41 (4.14–11.90) | 6 (4–7) | 0.79 | 0.09 | 0.30 |
| PC ae C36:2 | 17.10 ± 1.20 | 18.79 ± 1.32 | 16.95 ± 0.95 | 0.36 | 0.92 | 0.17 |
| PC ae C36:3 | 5.78 (3.30–8.37) | 4.86 (3.38–8.13) | 5.25 (3.30–7.10) | 0.59 | 0.28 | 0.77 |
| PC ae C36:4 | 3.85 (2.16–5.93) | 3.61 (2.16–5.81) | 3.87 (2.16–4.81) | 0.93 | 0.58 | 0.93 |
| PC ae C36:5 | 1.60 ± 0.13 | 1.55 ± 0.13 | 1.62 ± 0.10 | 0.77 | 0.99 | 0.51 |
| PC ae C38:0 | 2.86 ± 0.19AB | 3.02 ± 0.19 A | 2.65 ± 0.19 B | 0.57 | 0.43 | 0.004 |
| PC ae C38:1 | 3.30 (1.56–4.49) A | 2.78 (1.64–7.77) A | 2.54 (1.27–4.56) B | 0.67 | 0.03 | 0.07 |
| PC ae C38:2 | 14.40 (6.55–18.00) | 11.75 (8.09–28.00) | 12.00 (5.71–21.20) | 0.74 | 0.10 | 0.14 |
| PC ae C38:3 | 5.73 (2.46–7.57) | 4.89 (3.04–10.50) | 4.64 (2.53–7.61) | 0.93 | 0.17 | 0.26 |
| PC ae C38:4 | 7.97 (5.10–14.30) | 9.21 (5.50–14.80) | 8.22 (5.03–11.50) | 0.65 | 0.74 | 0.17 |
| PC ae C38:5 | 4.53 ± 0.32 | 4.82 ± 0.36 | 4.80 ± 0.28 | 0.56 | 0.53 | 0.94 |
| PC ae C38:6 | 1.84 ± 0.17 | 1.64 ± 0.16 | 1.76 ± 0.17 | 0.39 | 0.74 | 0.27 |
| PC ae C40:1 | 1.59± 0.10 AB | 1.67 ± 0.14 A | 1.44 ± 0.11 B | 0.66 | 0.34 | 0.01 |
| PC ae C40:2 | 1.31 (0.60–1.42) | 1.17 (0.76–1.95) | 1.12 (0.68–1.68) | 0.44 | 0.44 | 0.35 |
| PC ae C40:3 | 1.42 (0.69–1.66) A | 1.11 (0.71–2.86)AB | 1.00 (0.68–2.01) B | 0.38 | 0.02 | 0.15 |
| PC ae C40:4 | 4.85 (3.06–6.95) | 4.58 (2.72–9.79) | 4.22 (2.24–6.87) | 0.88 | 0.06 | 0.14 |
| PC ae C40:5 | 2.23. ± 0.18 | 2.28 ± 0.17 | 2.14 ± 0.15 | 0.88 | 0.73 | 0.26 |
| PC ae C40:6 | 1.81 ± 0.12 | 1.28 ± 0.15 | 1.40 ± 0.15 | 0.60 | 0.35 | 0.16 |
| PC ae C42:0 | 0.86 (0.61–1.08)AB | 0.90 (0.59–1.80) A | 0.88 (0.49–1.83) B | 0.23 | 0.88 | 0.04 |
| PC ae C42:1 | 0.81 (0.54–1.09) | 0.89 (0.52–1.90) | 0.82 (0.44–2.07) | 0.21 | 0.64 | 0.31 |
| PC ae C42:2 | 0.5 3(0.36–0.69) | 0.56 (0.25–0.82) | 0.45 (0.23–0.87) | 0.92 | 0.40 | 0.41 |
| PC ae C42:3 | 0.44 (0.27–0.84) | 0.43 (0.19–0.97) | 0.45 (0.16–0.91) | 0.80 | 0.60 | 0.86 |
| PC ae C42:4 | 0.32 (0.19–0.49)A | 0.27 (0.13–0.68)AB | 0.23 (0.10–0.48)B | 0.41 | 0.03 | 0.26 |
| PC ae C44:3 | 0.067 (0.03–0.10)A | 0.047 (0.03–0.09)AB | 0.050 (0.03–0.07)B | 0.18 | 0.03 | 0.62 |
| PC ae C44:4 | 0.092 (0.05–0.12) | 0.076 (0.06–0.12) | 0.067 (0.05–0.13) | 0.21 | 0.06 | 0.31 |
| PC ae C44:5 | 0.088 ± 0.01 A | 0.084 ± 0.01AB | 0.073 ± 0.00 B | 0.67 | 0.049 | 0.16 |
| PC ae C44:6 | 0.078 ± 0.01 | 0.079 ± 0.01 | 0.070 ± 0.01 | 0.93 | 0.38 | 0.26 |
| Total PC ae | 122.40 (63.36–140.49) | 106.24 (75.36–183.61) | 106.61 (71.82–143.31) | 0.89 | 0.28 | 0.36 |
Normally distributed data expressed as mean ± SE.
Non-parametric data expressed as median (min-max).
Superscript capital letters (A, B) denote significant differences between groups with different letters where a p-value <0.05 is considered significant.
No superscript letters in a row indicates no significant differences between groups for the measured parameter