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. 2024 Mar 15;19(3):e0299836. doi: 10.1371/journal.pone.0299836

Table 2. Age adjusted estimates for clinical characteristics related to metabolic syndrome by sex and race/ethnicity, adults with Metabolic Dysfunction-Associated Steatotic Liver Disease (MASLD), The National Health and Nutrition Examination Survey (NHANES III) 1988–1994 (n = 3,080).

Clinical Characteristics Males Females
White, non-Hispanics Black, non-Hispanics Mexican Americans White, non-Hispanics Black, non-Hispanics Mexican Americans
(n = 1,961) (n = 1,351) (n = 1,553) (n = 2,323) (n = 1,790) (n = 1,627)
Number of Metabolic Abnormalities, Mean (SE) 1.8 (0.04) 1.5 (0.04) * 1.9 (0.05) * 1.5 (0.06) 1.8 (0.03) * 2.1 (0.03) *
Metabolic Syndrome, % (SE) 27.9 (0.01) 21.4 (0.01) * 31.1 (0.01) 23.7 (0.01) 27.7 (0.01) * 35.6 (0.01) *
Central Obesity, % (SE) 31.1 (0.01) 26.6 (0.01) * 31.1 (0.02) 40.8 (0.01) 59.5 (0.01) * 60.4 (0.01) *
    Waist Circumference (inches), Mean (SE) 96.6 (0.3) 93.3 (0.3) * 96.1 (0.4) 87.7 (0.5) 93.9 (0.5) * 93.1 (0.4) *
Hypertriglyceridemia, % (SE) 40.8 (0.02) 27.0 (0.01) * 47.4 (0.02) * 26.7 (0.01) 19.6 (0.01) * 39.6 (0.01) *
    Triglyceridemia (mg/dL), Mean (SE) 161.0 (3.9) 128.5 (2.6) * 182.1 (4.4) * 130.8 (3.4) 111.1 (2.0) * 153.8 (3.2) *
Hypertension, % (SE) 38.0 (0.01) 46.1(0.01) * 36.8 (0.01) 30.3 (0.01) 43.3 (0.01) * 35.5 (0.01) *
    SBP (mmHg), Mean (SE) 106.1 (0.8) 108.6 (0.8) * 106.0 (0.8) 87.3 (0.6) 93.1 (0.6) * 89.8 (0.6) *
Dyslipidemia, % (SE) 38.2 (0.02) 24.2 (0.01) * 37.4 (0.02) 38.5 (0.02) 36.3 (0.01) 47.8 (0.02) *
    HDL (mg/dL), Mean (SE) 44.8 (0.5) 52.1 (0.5) * 45.3 (0.5) 55.6 (0.6) 57.1 (0.5) * 52.1 (0.5) *
Hyperglycemia, % (SE) 30.4 (0.01) 30.4 (0.01) 38.2 (0.02) * 17.8 (0.01) 25.9 (0.01) * 30.5 (0.01) *
    Plasma Glucose (mg/dL), Mean (SE) 100.1 (0.6) 101.9 (0.8) 105.8 (0.9) * 95.1 (0.7) 102.0 (1.5) * 102.2 (0.7) *

HDL, High-Density Lipoprotein Cholesterol; SBP, Systolic Blood Pressure

* P-value <0.05 for adults of the same sex in reference to white non-Hispanics

† (1) hyperglycemia (i.e., fasting blood glucose over 100 mg/dl, or pharmacological treatment), (2) dyslipidemia (i.e., fasting HDL cholesterol level less than 40 mg/dl, men, or 50 mg/dl, women, or pharmacological treatment) (3) hypertriglyceridemia (i.e., fasting triglyceride (TG) level over 150 mg/dl, or pharmacological treatment), (4) central obesity (i.e., waist circumference over 40 inches, men, or 35 inches, women), or (5) hypertension (i.e., systolic blood pressure (SBP) over 130 mmHg, or pharmacological treatment)

Three or more metabolic abnormalities