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. 2024 Mar 15;19(3):e0299836. doi: 10.1371/journal.pone.0299836

Table 3. The association between metabolic syndrome severity and odds of Metabolic Dysfunction-Associated Steatotic Liver Disease Occurrence in United States adults, the National Health and Nutrition Examination Survey (NHANES III) 1988–1994 (n = 10,605).

Metabolic Syndrome Severity Unadjusted Model 1 Model 2
OR (95% CI) OR (95% CI) OR (95% CI)
Low Reference Reference Reference
Moderate 1.69 (1.36 ⎯ 2.11) 1.80 (1.45 ⎯ 2.24) 1.26 (0.97 ⎯ 1.64)
High 3.67 (2.96 ⎯ 4.54) 3.99 (3.20 ⎯ 4.98) 2.27 (1.70 ⎯ 3.03)
Very High 6.08 (4.79 ⎯ 7.72) 6.60 (5.21 ⎯ 8.36) 3.12 (2.20 ⎯ 4.42)

Metabolic Syndrome Severity Group, the Metabolic Syndrome Z-score was transformed into four percentiles-based categories [low (0 – 50th), Moderate (>50th– 75th), High (>75th– 90th), and very-high (>90th)]

Model 1 = adjusted for age, sex, and race/ethnicity

Model 2 = Adjusted for age, sex, race/ethnicity, education level, access to health insurance, alcohol intake, smoking status, body mass index, abdominal obesity, physical activity, healthy eating index percentile, HOMA-IR, total cholesterol, and Aspartate Aminotransferase (AST)/alanine aminotransferase (ALT) Ratio

OR; odds ratio, CI; Confidence interval