Table 5.
Univariate and multivariate analysis of recurrence-free survival for HCC patients in the stabilized IPTW cohort.
| Univariate analysis | Multivariate analysis | |||||
|---|---|---|---|---|---|---|
| Characteristics | HR | 95% CI | P | HR | 95% CI | P |
| Group (3D vs.2D) | 0.72 | (0.61–0.85) | <0.001 | 0.71 | (0.61–0.84) | <0.001 |
| Age (≥60 vs. <60 y) | 0.85 | (0.71–1.02) | 0.078 | |||
| Sex (Female vs. Male) | 0.85 | (0.68–1.06) | 0.149 | |||
| Hepatitis (Presence vs. Absence) | 1.04 | (0.86–1.25) | 0.713 | |||
| Cirrhosis (Yes vs. No) | 1.08 | (0.91–1.27) | 0.388 | |||
| AFP (≥400 vs. <400 ng/mL) | 1.06 | (0.88–1.27) | 0.562 | |||
| Surgical approach (OH vs. LH) | 0.88 | (0.71–1.08) | 0.204 | |||
| Resection approach (AR vs. NAR) | 0.81 | (0.68–0.96) | 0.018 | 0.75 | (0.64–0.89) | 0.001 |
| Blood transfusion (Yes vs. No) | 1.24 | (1.01–1.54) | 0.045 | 1.19 | (0.97–1.46) | 0.091 |
| Resection margin (≥10 vs. <10 mm) | 1.01 | (0.82–1.26) | 0.896 | |||
| Differentiation (Poor vs. Well-Moderated) | 0.95 | (0.78–1.14) | 0.563 | |||
| MVI (Positive vs. Negative) | 1.04 | (0.87–1.24) | 0.674 | |||
| Tumor diameter (≥5 vs. <5 cm)a | 1.47 | (1.24–1.74) | <0.001 | 1.49 | (1.25–1.78) | <0.001 |
| Tumor number (Multiple vs. Single) | 1.33 | (1.07–1.66) | 0.011 | 1.33 | (1.07–1.65) | 0.010 |
a
Tumor diameter refers to the maximum tumor diameter that can be obtained at the time of preoperative evaluation.
2D, two-dimensional; 3D, three-dimensional; AFP, α-fetoprotein; AR, anatomical resection; HR, hazard ratio; IPTW, inverse probability of treatment weighting; LH, laparoscopic hepatectomy; MVI, microvascular invasion; NAR, nonanatomical resection; OH, open hepatectomy.