TABLE 1.
Summary of levels of transactivation of the wild-type and mutant Cps
| Plasmid | Fragment | Mutation | % of wild-type activity |
|---|---|---|---|
| pPDL84A | 8X E2REa | Wild type | 100 |
| pEFP 63 | Mutant 11 | 117 | |
| pEFP 32 | Mutant 3 | 23 | |
| pEFP 68 | Mutant 12 | 36 | |
| pPDL5 | Cp −1021 to +3 | Wild type | 100 |
| pEFP 52 | Mutant 11 | 40.3–63.3 | |
| pEFP 46 | Mutant 3 | 36.6–45.5 | |
| pEFP 56 | Mutant 12 | 0–36.2 | |
| pEFP 76 | Mutant CBF1 | 0–10.6 |
a
8X E2RE, a multimerized version of the EBNA2 response element corresponding to positions −330 to −430 and cloned into a reporter vector.