Table 4.
Magnitudes of CD4 T cell cytokine responses (% of CD4 T cells), by antigen class
Median % (interquartile range) n = 4 antigens per category | Absolute p (Mann-Whitney) | ||
---|---|---|---|
RVMA | Classical | ||
TNF | 0.15 (0.001, 0.41) | 0.19 (0.03, 0.56) | 0.1852 |
IFNγ | 0.01 (0.001, 0.165) | 0.08 (0.001, 0.33) | 0.0107 |
IL-17 | 0.46 (0.05, 0.80) | 0.05 (0.001, 0.28) | <0.0001 |
GM-CSF | 0.20 (0.001, 0.61) | 0.09 (0.001, 0.25) | 0.0735 |
Values shown for each cytokine and each antigen are median % of all CD4 T cells that express the specified cytokine. For statistical analyses, assays that yielded undetectable levels of the stated cytokine were assigned a value of 0.001%.