Table 2.
Canonical Pathway for CLEAR signaling
| Symbol | Entrez Gene Name | SNP variant | Beta coefficient | p-value | Location | Type(s) |
|---|---|---|---|---|---|---|
| FNIP1 | folliculin interacting protein 1 | rs11950815 | 3.66 | 1.63E-08 | Cytoplasm | other |
| GBA1 | glucosylceramidase beta 1 | rs12411216 | 5.71 | 8.69E-12 | Cytoplasm | enzyme |
| GUSB | glucuronidase beta | rs4718275 | 5.08 | 9.49E-38 | Cytoplasm | enzyme |
| ITPR3 | inositol 1,4,5-trisphosphate receptor type 3 | rs73743401 | 22.45 | 2.25E-08 | Cytoplasm | ion channel |
| PPP2R3A | protein phosphatase 2 regulatory subunit B''alpha | rs1393787 | 5.05 | 9.49E-38 | Nucleus | phosphatase |
| RALB | RAS like proto-oncogene B | rs6542581 | −3.91 | 1.28E-20 | Cytoplasm | enzyme |