Table 4.

Results of RAPID-HF randomized clinical trial

No	Title	NT-proBNP	V̇O2, AT	Peak V̇O2	V̇E/V̇CO2 slop	Change in KCCQ-OSS
1	Rate-Adaptive Atrial Pacing for Heart Failure With Preserved Ejection Fraction The RAPID-HF Randomized Clinical Trial [26]	Did not reveal any mean change from the beginning of the pacing-off/pacing-on phase to the end of that 4-week phase Pacing-off: − 88 pg/ml Pacing-on: − 36 pg/ml p = 0.53	Pacing-on: 10.7 ml/kg/min Pacing-off: 10.4 ml/kg/min p = 0.46	Pacing-on: 16.8 ml/kg/min Pacing-off: 16.5 ml/kg/m	Pacing-on: 34.9 Pacing-off: 34.2 p = 0.34	Pacing-on: 3.8 Pacing-off: 4.7 p = 0.86