Table 3.

Comparison of diagnostic yield of genetic tests in CMD and CM

Author	n			Diagnostic yield %
	Traditional method	Exome	Genetic panels	Traditional method	Exome	Genetic panels
Schofielda [28]	26(56)	44(56)	42(56)	46	79	75
O’Gradyb [30]	41(122)	12(22)	10(11)	33.6	54	91
Villc [29]	31(56)	8(12)	23(44)	55	67	52

The diagnostic yield of exome and genetic panels is higher than the traditional method for congenital muscular dystrophies and congenital myopathies. Diagnostic yield in Schofield’s study increased to 79%, assuming that patients diagnosed with CMA would also be diagnosed by genetic panels or WES. O’Grady’s study extends over a long period with patients widely evaluated, and genetic panels were done in 11 cases

^aCongenital muscular dystrophies and congenital myopathies (CMD) study

^bCongenital myopathies (CM) study

^cEarly onset myopathies’ study