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. 2024 Mar 15;4:49. doi: 10.1038/s43856-024-00481-3

Fig. 2. Enhanced sensitivity of digital composites to 1-year longitudinal progression compared to UPDRS pronation-supination score.

Fig. 2

a Digital pronation-supination composite scores significantly distinguished between baseline and 12-month visits in PD patients (n = 52), whereas no difference was seen in healthy participants (n = 35). b In contrast, MDS-UPDRS pronation-supination scores demonstrated no difference between baseline and 12-month visits in healthy or PD participants. c Similarly, digital toe-tapping composite scores significantly distinguished between baseline and 12-month visits in PD patients (n = 56), suggesting worsening performance, and significantly distinguished healthy participants (n = 35) in the opposite direction, suggesting improved performance. d MDS-UPDRS toe-tapping scores demonstrated no difference between baseline and 12-month visits in healthy or PD participants.