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. 2024 Mar 15;14:6271. doi: 10.1038/s41598-024-56804-w

Table 1.

Absolute recovery (%) of the analytical HPLC method used to quantify albendazole sulphoxide (ABZSO), albendazole sulphone (ABZSO2), and albendazole (ABZ) in human saliva and blood (DBS) samples.

Matrix Analytes Cnominal (µg/mL) Recovery (%) ± SDa Mean ± SD
SALIVA ABZSO 0.05 86.1 ± 10.0 90.3 ± 2.7
0.5 95.0 ± 7.2
1 89.6 ± 5.2
ABZSO2 0.05 89.8 ± 7.6 88.5 ± 1.4
0.5 86.5 ± 5.9
1 89.3 ± 8.7
ABZ 0.05 70.0 ± 6.2 71.9 ± 2.1
0.5 74.2 ± 10.9
1 71.6 ± 8.2
DBS ABZSO 0.2 94.7 ± 3.0 83.1 ± 11.4
0.6 71.9 ± 7.8
1 84.7 ± 2.4
ABZSO2 0.2 89.8 ± 7.6 88.5 ± 1.4
0.6 86.5 ± 5.9
1 89.3 ± 8.7
ABZ 0.2 91.3 ± 11.8 89.4 ± 2.1
0.6 89.7 ± 16.0
1 87.1 ± 2.0

aValues are expressed as arithmetic mean (n = 6) of samples obtained from different patients. Cnominal: nominal concentration.