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. 2024 Mar 15;14:6271. doi: 10.1038/s41598-024-56804-w

Table 3.

Interday precision of the analytical HPLC method used to quantify albendazole sulphoxide (ABZSO), albendazole sulphone (ABZSO2), and albendazole (ABZ) in saliva and blood (DBS) human samples.

Matrix Analyte Cnominal (µg/mL) Quantified concentration (µg/mL)a ± SD % CV
SALIVA ABZSO 0.05 0.046 ± 0.002 4.76
0.5 0.541 ± 0.06 10.1
1 0.931 ± 0.12 13.6
ABZSO2 0.05 0.044 ± 0.002 4.76
0.5 0.537 ± 0.054 10.1
1 1.077 ± 0.110 10.1
ABZ 0.05 0.054 ± 0.003 5.54
0.5 0.461 ± 0.06 13.5
1 0.957 ± 0.161 16.8
DBS ABZSO 0.2 0.166 ± 0.014 9.51
0.6 0.642 ± 0.091 11.2
2 1.987 ± 0.091 4.55
ABZSO2 0.2 0.192 ± 0.010 5.49
0.6 0.558 ± 0.097 16.6
2 2.017 ± 0.116 5.73
ABZ 0.4 0.395 ± 0.040 10.2
0.6 0.664 ± 0.035 11.9
2 2.03 ± 0.242 11.9

a Values are expressed as arithmetic mean (n = 9). Cnominal: nominal concentration.