Table 4.
Lower limit of quantification (LLOQ) of albendazole sulphoxide (ABZSO), albendazole sulphone (ABZSO2), and albendazole (ABZ), determined in different human biological matrixes: saliva, blood (DBS), and serum.
| Matrix | ABZSO | ABZSO2 | ABZ | |
|---|---|---|---|---|
| Saliva | LLOQ (µg/mL) | 0.01 | 0.05 | 0.05 |
| Accuracy (%RE) | 10.0 | 13.0 | 8.60 | |
| Precision (% CV) | 5.70 | 4.70 | 5.50 | |
| DBS | LLOQ (µg/mL) | 0.1 | 0.1 | 0.4 |
| Accuracy (%RE) | 13 | 10.6 | 8.20 | |
| Precision (% CV) | 12.6 | 12.1 | 10.1 | |
| Serum1 | LLOQ (µg/mL) | 0.025 | 0.025 | 0.025 |
| Accuracy (%RE) | 10.3 | 9.30 | 18.6 | |
| Precision (% CV) | 3.78 | 8.46 | 7.42 | |
1Data reported in Ceballos et al8.
Significant values are in [bold].