Fig. 5.

The Nanostring gene analysis of inflammatory genes in the dorsal root ganglion. The heatmap shows eight significant differential expression gene lists overlap genes between comparisons Day −7 (sham) vs. Day 0 (control) and Day 1 (UHF) vs. Day 0 (control). Among these, the gene expression of the below 7 genes, Cln3, Nfkbie, Cables1, Pik3r1, Vps4b, Tlr7, and Ezh2, indicate the potential UHF regulatory effects. The Nfkbie and Cln3 were upregulated after nerve injury in control group, but significantly downregulated by UHF treatment. The Tlr7, Pik3r1, Eh2, Vps4b, and Cables were downregulated after nerve injury in control group, while upregulated by UHF treatment. (n ​= ​3 for each group; ∗ indicated p ​< ​0.05).