Table 1.
Summary of patient baseline demographics and treatment characteristics
| Variable | All patients (n = 432) | 1 Resection (n = 329) | 2 Resections (n = 83) | 3 Resections (n = 20) |
|---|---|---|---|---|
| Age | ||||
| < 70 years | 351 | 251 | 80 | 20 |
| > 70 years | 81 | 78 | 3 | 0 |
| Gender | ||||
| Male | 281 | 220 | 51 | 10 |
| Female | 151 | 109 | 32 | 10 |
| WHO performance status | ||||
| PS = 0–1 | 401 | 310 | 73 | 18 |
| PS = 2–3 | 31 | 19 | 10 | 2 |
| MGMT Status | ||||
| Unmethylated | 171 | 122 | 43 | 6 |
| Methylated < 10% | 96 | 76 | 15 | 5 |
| Methylated 10–25% | 25 | 18 | 6 | 1 |
| Methylated > 25% | 40 | 28 | 8 | 4 |
| Not performed | 100 | 85 | 11 | 4 |
| Operative details for initial resection | ||||
| 5-ALA used | 374 | 281 | 74 | 19 |
| DTI used | 335 | 259 | 64 | 12 |
| iUSS used | 161 | 131 | 26 | 4 |
| Extent of resection | ||||
| GTR (100%) | 110 | 68 | 41 | 4 |
| NTR (> 95%) | 160 | 95 | 48 | 7 |
| STR (< 95) | 272 | 234 | 25 | 13 |
| Chemo-radiotherapy | ||||
| RT 60/30 + TMZ | 278 | 186 | 74 | 18 |
| RT 40/15 + TMZ | 24 | 19 | 4 | 1 |
| RT 60/30 alone | 21 | 18 | 3 | 0 |
| RT 40/15 alone | 29 | 28 | 1 | 0 |
| RT 30/15 alone | 4 | 4 | 0 | 0 |
| No CRT | 38 | 36 | 1 | 1 |
| Unknown | 38 | 38 | 0 | 0 |