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. 2024 Mar 15;4:47. doi: 10.1038/s43856-024-00477-z

Fig. 3. Mapping of immunodominant linear antibody epitopes on ACE2 complexed with SARS-CoV-2 receptor-binding domain molecular structure.

Fig. 3

a Crystal structure of the SARS-CoV-2 spike receptor-binding domain bound with ACE2 (PDB: 6M0J)23,25. ACE2 protein in dark green, RBD in orange, immunodominant peptide regions shaded red and labeled with peptide ID. b Closer view of the ACE2 enzyme catalytic site with residues found bound to an ACE2 enzyme drug inhibitor (MLN-4760) shaded in purple.