Table 1.
Baseline clinical characteristics and In-hospital management.
| Overall population | IPTW population | |||||
|---|---|---|---|---|---|---|
| DP-DES | BP-DES | p value | DP-DES | BP-DES | p value | |
| n = 374 | n = 246 | n = 498 | n = 491 | |||
| Age (years) | 67.2 ± 12.4 | 66.6 ± 12.5 | 0.550 | 66.3 ± 12.7 | 66.3 ± 12.2 | 0.984 |
| Male | 275 (73.5) | 178 (72.4) | 0.748 | 363 (72.8) | 369 (75.1) | 0.325 |
| BMI (Kg/m2) | 23.7 ± 3.3 | 24.0 ± 3.6 | 0.286 | 23.7 ± 3.2 | 23.9 ± 3.5 | 0.544 |
| Clinical presentation | 0.062 | 0.681 | ||||
| NSTEMI | 122 (32.6) | 63 (25.6) | 145 (29.2) | 136 (27.7) | ||
| STEMI | 252 (67.4) | 183 (74.4) | 353 (70.8) | 355 (72.3) | ||
| Cardiovascular risk factor | ||||||
| Hypertension | 204 (54.6) | 145 (58.9) | 0.280 | 274 (55.0) | 267 (54.3) | 0.825 |
| Diabetes mellitus | 127 (34.0) | 100 (40.7) | 0.091 | 187 (37.6) | 182 (37.0) | 0.612 |
| Chronic kidney disease | 38 (10.2) | 16 (6.5) | 0.114 | 42 (8.4) | 37 (7.6) | 0.742 |
| Current smoker | 137 (36.6) | 79 (32.1) | 0.248 | 183 (36.8) | 160 (32.6) | 0.189 |
| Previous PCI | 42 (11.2) | 28 (11.4) | 0.953 | 52 (10.5) | 51 (10.3) | 0.917 |
| Previous myocardial infarction | 56 (15.0) | 22 (8.9) | 0.027 | 65 (13.0) | 51 (10.4) | 0.472 |
| Peripheral artery disease | 11 (2.9) | 7 (2.9) | 0.945 | 14 (2.8) | 16 (3.2) | 0.900 |
| Previous history of stroke | 28 (7.5) | 22 (8.9) | 0.515 | 39 (7.9) | 39 (8.0) | 0.493 |
| Left ventricular ejection fraction (%) | 37.3 ± 15.0 | 37.1 ± 15.6 | 0.890 | 37.0 ± 14.9 | 36.9 ± 15.8 | 0.867 |
| Systolic blood pressure, mmHg | 73.1 ± 28.8 | 77.3 ± 30.2 | 0.079 | 76.6 ± 28.2 | 75.4 ± 30.6 | 0.546 |
| Diastolic blood pressure, mmHg | 46.9 ± 20.0 | 49.0 ± 19.3 | 0.195 | 49.1 ± 19.9 | 48.0 ± 19.7 | 0.351 |
| Heart rate, beat/min | 79.0 ± 34.1 | 77.1 ± 31.1 | 0.484 | 79.8 ± 33.4 | 76.2 ± 33.4 | 0.095 |
| Laboratory findings | ||||||
| Hemoglobin, g/dL | 13.1 ± 2.4 | 13.1 ± 2.2 | 0.960 | 13.2 ± 2.3 | 13.2 ± 2.1 | 0.819 |
| Creatinine, mg/dL | 1.4 ± 1.1 | 1.6 ± 1.6 | 0.265 | 1.4 ± 1.1 | 1.4 ± 1.2 | 0.972 |
| Glucose, mg/dL | 230.8 ± 119.2 | 236.3 ± 123.0 | 0.589 | 237.0 ± 134.6 | 237.9 ± 115.0 | 0.914 |
| Lactate, mmol/L | 1.8 (1.3 3.8) | 1.5 (0.9–2.8) | 0.011 | 1.7 (1.1–3.2) | 1.5 (0.9–2.7) | 0.385 |
| Peak CK-MB, ng/mL | 180.1 (50.0–300.0) | 205.9 (62.8–300.0) | 0.641 | 200.0 (63.2–300.0) | 221.6 (52.4–300.0) | 0.504 |
| Peak Troponin I, ng/mL | 18.4 (2.0–58.2) | 14.2 (1.1–66.3) | 0.283 | 19.2 (2.5–60.0) | 16.6 (1.5–78.2) | 0.433 |
| Undergoing CPR | 81 (21.7) | 39 (15.9) | 0.074 | 89 (17.8) | 96 (19.6) | 0.355 |
| Vasoactive Inotropic Score | 30.5 (10.0–83.6) | 20.0 (7.1–80.0) | 0.004 | 30.0 (10.0–75.0) | 26.6 (9.5–97.0) | 0.805 |
| In-hospital management | ||||||
| Mechanical ventilation | 229 (61.2) | 108 (43.9) | < 0.001 | 265 (53.3) | 261 (53.1) | 0.494 |
| Renal-replacement therapy | 71 (19.0) | 35 (14.2) | 0.124 | 80 (16.0) | 78 (15.9) | 0.759 |
| Mechanical circulatory support | 234 (62.6) | 123 (50.0) | 0.002 | 286 (57.4) | 276 (56.2) | 0.876 |
Data are n (%), mean ± standard deviation, or median (interquartile range).
BP-DES biodegradable polymer drug-eluting stent, BMI body-mass index, CABG coronary artery bypass grafting, CK-MB creatine kinase myocardial band, CPR cardiopulmonary resuscitation, DP-DES durable polymer drug-eluting stent, IPTW inverse probability of treatment weighting, PCI percutaneous coronary intervention, STEMI ST-segment elevation myocardial infarction, NSTEMI nonST-segment elevation myocardial infarction.