Table 2.
Clinical characteristics of psoriasis Patients with clear SARS-CoV-2 infection status.
| Characteristic | SARS-CoV-2 infection (n = 516) | SARS-CoV-2 non-infection (n = 71) | P-value |
|---|---|---|---|
| Subtype of psoriasis | |||
| Psoriasis vulgaris | 438 (84.9) | 59 (83.1) | 0.695 |
| Other subtypes of psoriasis* | 78 (15.1) | 12 (16.9) | |
| Course of psoriasis, (years) | |||
| ≤ 10 | 240 (46.5) | 38 (53.5) | 0.267 |
| > 10 | 276 (54.5) | 33 (46.5) | |
| Severity of psoriasis* | |||
| Mild | 105 (20.3) | 22 (31.0) | 0.041 |
| Moderate to severe | 411 (79.7) | 49 (69.0) | |
| Nail impairment | |||
| Yes | 254 (49.2) | 26 (36.6) | 0.046 |
| No | 262(50.8) | 45 (63.4) | |
| Unhealthy lifestyle habits* | |||
| Yes | 334 (64.7) | 48 (67.6) | 0.634 |
| No | 182 (35.3) | 23 (32.4) | |
| Mental stress exacerbates psoriasis | |||
| Yes | 43 (8.3) | 1 (1.4) | 0.038 |
| No | 473 (91.7) | 70 (98.6) | |
| Infection exacerbates psoriasis | |||
| Yes | 130 (25.2) | 6 (8.5) | 0.002 |
| No | 386 (74.8) | 65 (91.5) | |
| Psoriasis treatment | |||
| Oral systemic treatment | 71 (13.8) | 8 (11.3) | 0.933 |
| Biological treatment | 330 (63.9) | 47 (66.2) | |
| Non-systemic treatment | 82 (15.9) | 12 (16.9) | |
| Not receiving treatment | 33 (6.4) | 4 (5.6) | |
| Biologics | |||
| Anti TNF-α | 23 (4.5) | 6 (8.5) | 0.129 |
| Anti IL-12/23 | 65 (12.6) | 13 (18.3) | |
| Anti IL-23 | 29 (5.6) | 1 (1.4) | |
| Anti IL-17 | 213 (41.3) | 27 (38.0) | |
| Oral systemic treatment | |||
| TCM* | 36 (7.0) | 3 (4.2) | 0.306 |
| TYK2* | 3 (0.6) | 2 (2.8) | |
| Cyclosporin | 2 (0.4) | 0 (0.0) | |
| Acitretin | 21 (4.1) | 3 (4.2) | |
| Methotrexate | 8 (1.6) | 0 (0.0) | |
| Glucocorticosteroid | 4 (0.8) | 0 (0.0) | |
Values are presented as n (%) unless stated otherwise. Other subtypes of psoriasis*: include Psoriasis Arthritis, Pustular Psoriasis, Erythrodermic Psoriasis. Severity of psoriasis*: mild, BSA (body surface area) ≤ 3%; moderate to severe, BSA > 3%. Unhealthy lifestyle habit*: include smoking, alcohol consumption, bad diet, unlike exercising, poor sleep quality and others. TCM*: Traditional Chinese Medicine; TYK2*: TYK2, tyrosine kinase 2; TNF-α, tumor necrosis factor alpha; IL-12/23, interleukin-12 and 23; IL-23, interleukin-23; IL-17, interleukin-17.