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. 2024 Feb 20;27(3):109287. doi: 10.1016/j.isci.2024.109287

Table 5.

Patients with respiratory depression at each time point

Overall (n = 167) Morphine (n = 83) Nalbuphine (n = 84) p value
PACU 19 (11.4) 15 (18.1) 4 (4.8) 0.014
PACU + 15 min 13 (7.8) 13 (15.7) 0 (0.0) <0.001
PACU + 30 min 2 (1.3) 2 (2.7) 0 (0.0) 0.221
PACU + 45 min 1 (0.7) 1 (1.4) 0 (0.0) 1
PACU + 60 min 1 (0.7) 1 (1.4) 0 (0.0) 1
Total 36 32 4

Value is number (percentage, %). Respiratory depression was defined as RR was less than lower limit (1st percentile) for respiratory rate in 2-year-old is 18, 3-year-old is 17, and 4- to 5-year-old is 17.