Table 6.
Comparison of studies reporting complications after PMPRT
| Study first author, institution | Total number of PMPRT courses | Reconstruction type at time of PMPRT | Years treated | Median follow-up (mo) | Follow-up time measured from | MRC crude incidence* N (%) |
|---|---|---|---|---|---|---|
| Current study | 73 | 30 implants, 14 expanders, 29 flaps | 2013-2021 | 42 | Date of PMPRT start | 9 (12.3) |
| Current study (implant/expander only) | 44 | 14 expanders, 30 implants | 2013-2021 | 42 | Date of PMPRT start | 7 (15.9) |
| Smith, Mayo Clinic15 | 51 | 51 expanders | 2015-2017 | 16 | Date of PMPRT end | 11 (21.6) |
| Luo, Memorial Sloan Kettering14 | 26 | 25 implants, 1 flap | 2013-2015 | 35 | Date of PMPRT end | 7 (26.9) |
| Naoum, Mass General Hospital12 | 17 | 14 implants, 3 expanders | 2000-2019 | 84 | Date of diagnosis | 9 (52.9) |
| Jimenez, Mass General Hospital13 | 49 | (38 implants, 11 expanders) | 2011-2016 | 55 | Date of PMPRT start | 14 (28.6) |
Abbreviations: MRC = major reconstruction complication; PMPRT = postmastectomy proton radiation therapy.
⁎
Studies have varying definitions and terminology to describe MRC. We applied our definition of MRC to the data available in each study for the purpose of comparison. Studies also had varying inclusion criteria. This table includes courses of PMPRT where there was either implant, expander, or flap in place at the time of PMPRT delivery. It does not include patients who had radiation reconstruction complications before undergoing PMPRT or patients who had no reconstruction at the time of PMPRT.