Fig. 2.
Association between Trp and different disease activity indices in cohort 1. a-c, Negative relationships between Trp and CDAI, total Mayo, and BASDAI for CD, UC, and AxSpA, respectively. d and e, The relationship between DAS28 and Trp in RA varies by disease entity, with a detectable negative association between DAS28 and Trp in patients with RAneg but not RApos. f, No significant association between Trp and PASI was detected in patients with Pso. All available observations are included in each plot, and the regression line is depicted in black. LMM: Linear mixed model, n = total number of patients. Shaded areas represent the 95% confidence intervals of the plotted data. Confidence intervals from LMM: CDAI: −220 to −55, Total Mayo: −13 to −6.1, BASDAI: −5.5 to −0.79, DAS28 (RAneg): −1.2 to −0.25, DAS28 (RApos): −0.49 to 0.18, PASI: −26 to 28. DAS28 was log10-transformed in the LMM.