Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Permeability and efflux ratio of the payloads 10 and 11 measured in flux assays with Caco-2 cells. The values represent the mean value of at least two independent assays performed in triplicates (n = 3).
| Compound | Caco-2 Flux Papp B-A | Caco-2 Flux Papp A-B | Caco-2 flux efflux ratio |
|---|---|---|---|
| 10 | 179.7 | 3.8 | 129.1 |
| 11 | 303.0 | 34.8 | 8.7 |
