Table 4.
Prediction of the treatment factor for mortality in patients with ILD and NSCLC assessed using the Cox proportional-hazards model
| Variable | Univariate analysis | Multivariate analysis | ||||
|---|---|---|---|---|---|---|
| HR | 95% CI | P Value | HR | 95% CI | P Value | |
| ILD treatment | ||||||
| Antifibrotics | 0.714 | 0.420–1.214 | 0.214 | |||
| Corticosteroid ± IS | 2.058 | 1.218–3.476 | 0.007 | 1.162 | 0.503–2.685 | 0.726 |
| Acute exacerbation | 2.124 | 1.147–3.931 | 0.017 | 1.282 | 0.542–3.034 | 0.572 |
| Initial treatment for LC | ||||||
| Surgery | 0.198 | 0.092–0.423 | < 0.001 | 0.235 | 0.106–0.522 | < 0.001 |
| Chemotherapy | 2.334 | 1.276–4.269 | 0.006 | 1.290 | 0.682–2.439 | 0.434 |
| Radiotherapy | 0.781 | 0.412–1.480 | 0.449 | |||
| CCRT | 0.916 | 0.222–3.776 | 0.904 | |||
HR, hazard ratio; CI, confidence interval; SqCC, squamous cell carcinoma; ADC, adenocarcinoma; TLC, total lung capacity; FVC, forced vital capacity; FEV1, forced expiratory volume in 1 second; DLco, diffusing capacity for carbon monoxide; IPF, idiopathic pulmonary fibrosis; ILD, interstitial lung disease; KL-6, Krebs von den Lungen-6; IS, immunosuppressant; CCRT, concurrent chemoradiation therapy
Bold values denote statistical significance at the p < 0.05 level