TABLE 2.
Statistics on arsenic in the clinical treatment of recurrent APL.
| APL recurrent (case) | Dose of arsenic | Complete response rate | Author |
|---|---|---|---|
| 20 | As2O3 10 mg/d (adult) and 0.16 mg/kg (children) | 60% (12 cases) | Zhang (2017) |
| 8 | As2O3 10 mg/d | 100% (8 cases) | Kwong et al. (2001) |
| 47 | As2O3 10 mg/d | 85.1% (40 cases) | Niu et al., (1999) |
| 40 | As2O3 0.15 mg/kg/d | 85% (34 cases) | Soignet et al. (2001) |
| 12 | 0.06–0.2 mg/kg ATO | 91.67% (11 cases) | Soignet et al. (1998) |
| 388 | As2O3 10 mg/d | 74.13% | Ma et al. (2005) |
| 15 | As2O3 10 mg/d | 100% | Zhang et al. (2001) |
| 41 | Treatment group: arsenious acid 5 mg/d (2 children 2 mg/d–3 mg/d); control group: arsenious acid 10 mg/d | Treatment group: 80% | Guan et al. (2003) |
| Control group: 81.9% |