Table 1.
NHW, % (n=259 805) | NHB, % (n=64 456) | Hispanic, % (n=24 025) | Absolute standardized differences | ||
---|---|---|---|---|---|
NHW vs NHB | NHW vs Hispanic | ||||
Age, y, mean±SD | 64.5±14.9 | 59.6±14.3 | 56.4±16.5 | 0.33* | 0.52* |
Female sex | 44.9 | 47.5 | 42.4 | 0.05 | 0.05 |
Comorbidities | |||||
Hypertensive diseases | 27.0 | 31.1 | 23.1 | 0.09 | 0.09 |
Chronic ischemic heart disease | 11.3 | 8.6 | 7.1 | 0.09 | 0.14* |
Acute myocardial infarction | 2.7 | 2.8 | 2.2 | 0.01 | 0.03 |
Hyperlipidemia | 19.5 | 15.9 | 12.9 | 0.09 | 0.18* |
Atherosclerosis | 2.6 | 2.3 | 1.9 | 0.02 | 0.04 |
Arterial thrombosis | 0.8 | 0.7 | 0.6 | 0.01 | 0.03 |
Seizures | 2.0 | 2.5 | 2.0 | 0.04 | <0.01 |
Parkinson disease | 0.9 | 0.3 | 0.4 | 0.08 | 0.06 |
Multiple sclerosis | 0.3 | 0.3 | 0.1 | 0.01 | 0.04 |
Alzheimer disease | 0.6 | 0.4 | 0.4 | 0.02 | 0.03 |
Hemiplegia | 0.5 | 0.6 | 0.6 | 0.01 | 0.02 |
Paraplegia | 0.2 | 0.3 | 0.2 | 0.02 | <0.01 |
Peripheral neuropathy | 2.9 | 2.2 | 2.2 | 0.03 | 0.045 |
Neurogenic bladder | 0.4 | 0.3 | 0.4 | 0.02 | 0.01 |
Neurogenic bowel | 0.1 | 0.1 | 0.1 | 0.01 | 0.01 |
Constipation | 4.9 | 5.1 | 4.9 | 0.01 | <0.01 |
Type 1 diabetes | 1.4 | 1.8 | 1.7 | 0.03 | 0.02 |
Type 2 diabetes | 12.9 | 16.7 | 15.9 | 0.11* | 0.09 |
Obesity | 6.4 | 6.7 | 6.1 | 0.01 | 0.01 |
Depression | 7.8 | 5.6 | 6.0 | 0.09 | 0.07 |
Anxiety | 7.8 | 4.3 | 5.4 | 0.15* | 0.10 |
Sleep disorders | 7.5 | 5.9 | 5.6 | 0.06 | 0.07 |
Chronic obstructive pulmonary disease | 6.1 | 4.8 | 2.3 | 0.06 | 0.12* |
Asthma | 3.0 | 4.1 | 2.6 | 0.06 | 0.03 |
Acute kidney failure | 5.3 | 7.5 | 5.3 | 0.09 | <0.01 |
Chronic kidney disease | 7.2 | 10.6 | 7.3 | 0.12 | <0.01 |
Benign prostatic hyperplasia | 3.5 | 2.2 | 2.2 | 0.08 | 0.08 |
Neoplasm | 14.1 | 10.3 | 9.3 | 0.12* | 0.15* |
Prior medication use | |||||
Anticonvulsants | 11.1 | 11.4 | 10.6 | 0.01 | 0.02 |
CNS stimulants | 2.0 | 1.2 | 2.0 | 0.07 | <0.01 |
SSRI/SNRIs | 13.4 | 9.0 | 10.0 | 0.14* | 0.11* |
Laxatives | 16.8 | 18.7 | 16.6 | 0.05 | 0.01 |
α Blockers | 4.7 | 3.7 | 3.4 | 0.05 | 0.06 |
Urinary antispasmodic | 7.2 | 10.6 | 7.3 | 0.12 | <0.01 |
Melatonin | 3.4 | 2.7 | 3.4 | 0.04 | <0.01 |
Tizanidine | 1.0 | 0.8 | 0.8 | 0.02 | 0.02 |
Baclofen | 1.0 | 1.0 | 1.0 | 0.01 | 0.01 |
Insulin | 9.6 | 12.7 | 12.3 | 0.10* | 0.09 |
Prior clinical data | |||||
Hemoglobin A1c | |||||
0%–5.70% | 3.7 | 4.0 | 3.1 | 0.02 | 0.04 |
5.70%–6.50% | 4.4 | 5.6 | 4.0 | 0.06 | 0.02 |
6.50%–9.0% | 4.6 | 5.8 | 4.5 | 0.05 | <0.01 |
>9.0% | 2.0 | 3.3 | 3.1 | 0.08 | 0.07 |
Systolic blood pressure, mm Hg | |||||
<140 | 29.1 | 23.1 | 18.0 | 0.14* | 0.26* |
140–180 | 22.5 | 21.5 | 13.1 | 0.03 | 0.25* |
180–220 | 5.4 | 7.7 | 3.7 | 0.09 | 0.08 |
>220 | 1.3 | 0.6 | 0.6 | 0.07 | 0.01 |
LDL cholesterol in serum or plasma, mg/dL | 13.3 | 13.5 | 9.7 | 0.15 | 0.01 |
0–70 | 4.4 | 3.7 | 3.3 | 0.04 | 0.06 |
71–189 | 10.3 | 10.3 | 6.8 | 0.02 | 0.10* |
>190 | 0.4 | 0.5 | 0.3 | 0.02 | <0.01 |
Prior health care use | |||||
Prior hospitalization | 23.3 | 19.6 | 21.3 | 0.09 | 0.04 |
Prior data were collected in the year preceding the indexed stroke. CNS indicates central nervous system; NHB, non‐Hispanic Black; NHW, non‐Hispanic White; SNRI, serotonin–norepinephrine reuptake inhibitor; and SSRI, selective serotonin reuptake inhibitor.
Clinically important differences based on absolute standardized differences ≥0.1.