Table 3.
Outcomes
| Outcomes | Overall N=291 | Optimal N=103 | Mixed N=125 | Poor N=63 | P value |
|---|---|---|---|---|---|
| In‐hospital outcomes | |||||
| Length of stay, d | 2 (1–3) | 1 (1–2) | 2 (1–4) | 2 (1–5) | 0.08 |
| In‐hospital mortality | 1 (0.3) | 1 (0.9) | 0 (0) | 0 (0) | … |
| TMPG, mm Hg | 4.2 [1.9] | 3.0 [0.9] | 4.5 [2.0] | 5.7 [2.0] | <0.001* |
| TMPG≥5, mm Hg | 99 (34.0) | 0 (0) | 54 (43.2) | 45 (71.4) | <0.001* |
| MR≥ moderate | 67 (23.1) | 0 (0) | 27 (21.6) | 40 (63.5) | <0.001* |
| TR≥ moderate | 95 (32.6) | 0 (0) | 44 (35.2) | 51 (81.0) | <0.001* |
| 30‐d outcomes | |||||
| Mortality | 10 (3.4) | 2 (1.9) | 4 (3.2) | 4 (3.2) | 0.31 |
| HFH | 6 (2.0) | 0 (0) | 4 (3.2) | 2 (3.2) | 0.18 |
| New York Heart Association functional class III or IV | 32 (15.2) | 6 (8.1) | 15 (15.6) | 11 (27.5) | 0.17 |
| LA volume, mL | 121.8 [49.6] | 116.8 [41.0] | 123.1 [55.4] | 127.6 [50.0] | 0.47 |
| LAVI, mL/m2 | 68.1 [25.7] | 64.2 [21.5] | 68.4 [28.1] | 73.9 [26.3] | 0.14 |
| Pulmonary artery systolic pressure, mm Hg | 47.2 [14.5] | 44.1 [13.8] | 46.5 [14.3] | 53.8 [14.4] | 0.002* |
| Left ventricle ejection fraction (%) | 48.1 [14.7] | 49.6 [13.0] | 46.4 [15.7] | 49.2 [15.2] | 0.25 |
| LVIDs, cm | 3.7 [1.1] | 3.5 [0.9] | 3.8 [1.2] | 3.8 [1.1] | 0.22 |
| LVIDd, cm | 5.1 [0.9] | 5.0 [0.8] | 5.2 [0.9] | 5.1 [0.9] | 0.26 |
| MR≥moderate | 89 (34.9) | 16 (17.6) | 45 (42.4) | 28 (53.8) | 0.005* |
| TMPG, mm Hg | 4.4 [2.2] | 3.4 [1.4] | 4.6 [2.3] | 5.9 [2.4] | 0.001* |
| TR severity ≥moderate | 96 (37.6) | 9 (10.1) | 42 (37.5) | 35 (64.9) | <0.001* |
| 1‐y outcomes | |||||
| Mortality | 62 (21.3) | 7 (6.8) | 34 (27.2) | 21 (33.3) | <0.001* |
| HFH | 34 (11.7) | 3 (2.9) | 18 (14.4) | 13 (20.6) | 0.001* |
| Composite | 85 (29.2) | 10 (9.7) | 45 (36.0) | 30 (47.6) | <0.001* |
| LA volume, mL | 119.0 [44.5] | 113.7 [39.2] | 123.6 [49.7] | 128.2 [44.0] | 0.30 |
| LAVI, mL/m2 | 64.6 [24.9] | 61.6 [19.9] | 67.3 [29.5] | 69.2 [25.1] | 0.32 |
| LVIDs, cm | 3.6 [1.1] | 3.4 [1.0] | 3.8 [1.2] | 3.7 [1.0] | 0.07 |
| LVIDd, cm | 5.1 [0.9] | 5.0 [0.8] | 5.2 [1.0] | 5.1 [0.7] | 0.43 |
| MR severity ≥moderate | 65 (35.1) | 16 (21.3) | 33 (42.3) | 16 (50.0) | 0.004* |
| TMPG, mm Hg | 4.2 [2.2] | 3.6 [1.8] | 4.5 [2.3] | 5.3 [2.3] | 0.002* |
| TR severity ≥moderate | 43 (26.3) | 11 (15.8) | 20 (27.0) | 13 (50.0) | <0.001* |
| 2‐y outcomes | |||||
| Mortality | 84 (28.9) | 11 (10.7) | 46 (36.8) | 27 (42.9) | <0.001* |
| HFH | 46 (15.8) | 6 (5.8) | 23 (18.4) | 17 (27.0) | <0.001* |
| Composite | 113 (38.8) | 17 (16.5) | 58 (46.4) | 38 (60.3) | <0.001* |
| Last follow‐up | |||||
| Mortality | 140 (48.1) | 34 (33.0) | 66 (52.8) | 40 (63.5) | <0.001* |
| HFH | 59 (20.3) | 10 (9.7) | 29 (23.2) | 20 (31.7) | 0.002* |
| Composite | 169 (58.1) | 40 (38.8) | 80 (64.0) | 49 (77.8) | <0.001* |
| Mitral valve reintervention | 9 (3.3) | 2 (2.1) | 4 (3.3) | 3 (5.0) | 0.60 |
Values are expressed as mean [SD] or N (%). HFH indicates heart failure hospitalization; LA, left atrium; LAVI, left atrium volume index; LVIDs/d, left ventricle internal diameter (systole/diastole); MR, mitral regurgitation; TMPG, transmitral mean pressure gradient; and TR, tricuspid regurgitation.
*
P value is significant if <0.05.