Table 3.

Association of risk of hospitalisation and death as a result of a (non-COVID-19) infectious disease (defined as ICD-9 and ICD-10 codes A00–B99, J00–J06, J09–J18, and J20–J22) with APOL1 genotypes compared to G0/G0, adjusted for age, sex, Townsend deprivation index, and genetic principal components 1–4.

Genotype	n (total)	n (hospitalisation) (%)	Odds ratio	p	n (death) (%)	Odds ratio	p
G0/G0	2853	666 (23.3%)	1.0 (ref)		10 (0.4%)	1.0 (ref)
G0/G1	2273	517 (22.7%)	0.9 (0.8–1.1)	0.35	10 (0.4%)	1.0 (0.4–2.5)	0.95
G0/G2	1219	269 (22.1%)	0.9 (0.8–1.1)	0.27	5 (0.4%)	1.0 (0.3–2.8)	0.94
G1/G1	644	148 (23.0%)	0.9 (0.7–1.1)	0.37	1 (0.2%)	0.5 (0.5–2.2)	0.39
G1/G2	320	101 (31.6%)	1.4 (1.1–1.9)	0.007	1 (0.3%)	0.9 (0.1–4.0)	0.91
G2/G2	153	33 (21.6%)	0.9 (0.6–1.3)	0.55	0 (0.0%)	0.8 (0.0–6.4)	0.88

p values < 0.05 are shown in bold. The G1/G2 genotype was associated with hospitalisation as a result of a (non-COVID-19) infectious disease.