Table 4.

Association of risk of hospitalisation and death as a result of COVID-19 (defined as ICD-10 code U071) with APOL1 genotypes compared to G0/G0, adjusted for age, sex, Townsend deprivation index, and genetic principal components 1–4.

Genotype	n (total)	n (hospitalisation) (%)	Odds ratio	p	n (death) (%)	Odds ratio	p
G0/G0	2853	54 (1.9%)	1.0 (ref)		14 (0.5%)	1.0 (ref)
G0/G1	2273	49 (2.2%)	1.1 (0.7–1.6)	0.72	12 (0.5%)	1.3 (0.6–2.9)	0.54
G0/G2	1219	23 (1.9%)	1.0 (0.6–1.6)	0.87	5 (0.4%)	1.0 (0.3–2.6)	0.99
G1/G1	644	11 (1.7%)	0.8 (0.4–1.6)	0.58	2 (0.3%)	0.9 (0.2–3.3)	0.93
G1/G2	320	15 (4.7%)	2.3 (1.2–4.1)	0.01	8 (2.5%)	6.6 (2.5–16.7)	0.0003
G2/G2	153	2 (1.3%)	0.8 (0.2–2.4)	0.74	1 (0.7%)	2.4 (0.3–10.1)	0.38

p values < 0.05 are shown in bold. The G1/G2 genotype was associated with hospitalisation and death as a result of a COVID-19.