Table 2.

Inflammatory cytokines as intermediates in causal effects of pancreatitis on gut microbiota

Exposure	βe-i	Intermediate	βi-o	Outcome	βe-o	β	SE	Intermediate ratio (%)
AICP	0.025	Pyruvate	0.286	genus.Eggerthella	0.067	0.007	0.013	10.4
AP	− 0.051	Free cholesterol in very large HDL	0.097	genus.Candidatus soleaferrea	− 0.100	− 0.005	0.003	0.5

AICP alcohol-induced chronic pancreatitis, AIAP alcohol-induced acute pancreatitis, SE standard error